“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy

Background: In vivo reflectance confocal microscopy (RCM) is a novel non-invasive diagnostic tool, which is used to differentiate skin lesions. Even in lesions with similar dermatoscopic images, RCM may improve diagnostic accuracy. Methods: Three sets of false ‘’twin lesions’’ with similar macro...

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Autores principales:	Secil Saral, Daniela Hartmann, Valerie Letulè, Thomas Ruzicka, Cristel Ruini, Tanja von Braunmühl
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2017
Materias:	reflectance confocal microscopy skin imaging clinical diagnosis dermatoscopy nevus melanoma Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/1b06b9913a6343e192508d565cb83bf4
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spelling	oai:doaj.org-article:1b06b9913a6343e192508d565cb83bf42021-11-17T08:30:55Z“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy2160-9381https://doaj.org/article/1b06b9913a6343e192508d565cb83bf42017-02-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/152https://doaj.org/toc/2160-9381 Background: In vivo reflectance confocal microscopy (RCM) is a novel non-invasive diagnostic tool, which is used to differentiate skin lesions. Even in lesions with similar dermatoscopic images, RCM may improve diagnostic accuracy. Methods: Three sets of false ‘’twin lesions’’ with similar macroscopic and dermatoscopic images are matched. All lesions are evaluated with RCM and lesions are excised for further evaluation. Corresponding features in confocal images, dermatoscopy and histopathology are discussed. Results: In all matched pairs, one of the lesions was diagnosed as melanoma with the observation of melanoma findings such as: epidermal disarray, pagetoid cells in epidermis and cellular atypia at the junction. Benign lesions were differentiated easily with RCM imaging. Conclusion: Examining dermatoscopically difficult and/or similar lesions with RCM facilitates diagnostic and therapeutic decision making. Using RCM in daily practice may contribute to a decrease in unnecessary excisions. Secil SaralDaniela HartmannValerie LetulèThomas RuzickaCristel RuiniTanja von BraunmühlMattioli1885articlereflectance confocal microscopyskin imagingclinical diagnosisdermatoscopynevusmelanomaDermatologyRL1-803ENDermatology Practical & Conceptual (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	reflectance confocal microscopy skin imaging clinical diagnosis dermatoscopy nevus melanoma Dermatology RL1-803
spellingShingle	reflectance confocal microscopy skin imaging clinical diagnosis dermatoscopy nevus melanoma Dermatology RL1-803 Secil Saral Daniela Hartmann Valerie Letulè Thomas Ruzicka Cristel Ruini Tanja von Braunmühl “Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
description	Background: In vivo reflectance confocal microscopy (RCM) is a novel non-invasive diagnostic tool, which is used to differentiate skin lesions. Even in lesions with similar dermatoscopic images, RCM may improve diagnostic accuracy. Methods: Three sets of false ‘’twin lesions’’ with similar macroscopic and dermatoscopic images are matched. All lesions are evaluated with RCM and lesions are excised for further evaluation. Corresponding features in confocal images, dermatoscopy and histopathology are discussed. Results: In all matched pairs, one of the lesions was diagnosed as melanoma with the observation of melanoma findings such as: epidermal disarray, pagetoid cells in epidermis and cellular atypia at the junction. Benign lesions were differentiated easily with RCM imaging. Conclusion: Examining dermatoscopically difficult and/or similar lesions with RCM facilitates diagnostic and therapeutic decision making. Using RCM in daily practice may contribute to a decrease in unnecessary excisions.
format	article
author	Secil Saral Daniela Hartmann Valerie Letulè Thomas Ruzicka Cristel Ruini Tanja von Braunmühl
author_facet	Secil Saral Daniela Hartmann Valerie Letulè Thomas Ruzicka Cristel Ruini Tanja von Braunmühl
author_sort	Secil Saral
title	“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
title_short	“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
title_full	“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
title_fullStr	“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
title_full_unstemmed	“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy
title_sort	“twin lesions”: which one is the bad one? improvement of clinical diagnosis with reflectance confocal microscopy
publisher	Mattioli1885
publishDate	2017
url	https://doaj.org/article/1b06b9913a6343e192508d565cb83bf4
work_keys_str_mv	AT secilsaral twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy AT danielahartmann twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy AT valerieletule twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy AT thomasruzicka twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy AT cristelruini twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy AT tanjavonbraunmuhl twinlesionswhichoneisthebadoneimprovementofclinicaldiagnosiswithreflectanceconfocalmicroscopy
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“Twin lesions”: Which one is the bad one? Improvement of clinical diagnosis with reflectance confocal microscopy

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