APOBEC3G-depleted resting CD4+ T cells remain refractory to HIV1 infection.
<h4>Background</h4>CD4+ T lymphocytes are the primary targets of HIV1 but cannot be infected when fully quiescent, due to a post-entry block preventing the completion of reverse transcription. Chiu et al. recently proposed that this restriction reflects the action of APOBEC3G (A3G). They...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2009
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| Acceso en línea: | https://doaj.org/article/1b1000cfba5c4167bed75b030dedd744 |
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