TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes

TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes

Abstract Potassium channels from prokaryotes and eukaryotes are usually recognized by a typical amino acid sequence TXTGY(F)G representing the ionic selectivity filter. Using a screening approach with ion channel family profiles but without the above motif, we identified a gene in Trypanosoma brucei...

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Autores principales: Michael E. Steinmann, Remo S. Schmidt, Peter Bütikofer, Pascal Mäser, Erwin Sigel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/1b1429f81af046fc82b5172f1e3cea90
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