Evaluation of intralesional propranolol for periocular capillary hemangioma

Ahmed Awadein, Mohamed A FakhryCairo University Faculty of Medicine, Cairo, EgyptBackground: The purpose of this study was to evaluate the use of intralesional propranolol injection in the management of periocular capillary hemangioma.Methods: A prospective study was performed in 22 consecutive pati...

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Autores principales: Awadein A, Fakhry MA
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Lenguaje:EN
Publicado: Dove Medical Press 2011
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Acceso en línea:https://doaj.org/article/1b20246580db44068a0936dc11dba58d
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spelling oai:doaj.org-article:1b20246580db44068a0936dc11dba58d2021-12-02T11:17:57ZEvaluation of intralesional propranolol for periocular capillary hemangioma1177-54671177-5483https://doaj.org/article/1b20246580db44068a0936dc11dba58d2011-08-01T00:00:00Zhttp://www.dovepress.com/evaluation-of-intralesional-propranolol-for-periocular-capillary-heman-a8077https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ahmed Awadein, Mohamed A FakhryCairo University Faculty of Medicine, Cairo, EgyptBackground: The purpose of this study was to evaluate the use of intralesional propranolol injection in the management of periocular capillary hemangioma.Methods: A prospective study was performed in 22 consecutive patients with periocular hemangioma. Twelve patients underwent intralesional propranolol injection and ten patients underwent intralesional triamcinolone injection. The size of the lesion was measured serially every week during the first month, every 2 weeks for the second month, and then monthly for another 2 months. The refractive error and degree of ptosis if present were measured before injection and at the end of the study.Results: There was reduction in the size of hemangioma, astigmatic error, and degree of ptosis in both groups. The difference in outcome between both groups was not statistically significant. Rebound growth occurred in 25% of the propranolol group and 30% of the steroid group but responded to reinjection. No adverse effects were reported during or after intralesional propranolol injection.Conclusion: Intralesional propranolol injection is an alternative and effective method for treatment of infantile periocular hemangioma.Keywords: propranolol, intralesional, periocular capillary hemangiomaAwadein AFakhry MADove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1135-1140 (2011)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Awadein A
Fakhry MA
Evaluation of intralesional propranolol for periocular capillary hemangioma
description Ahmed Awadein, Mohamed A FakhryCairo University Faculty of Medicine, Cairo, EgyptBackground: The purpose of this study was to evaluate the use of intralesional propranolol injection in the management of periocular capillary hemangioma.Methods: A prospective study was performed in 22 consecutive patients with periocular hemangioma. Twelve patients underwent intralesional propranolol injection and ten patients underwent intralesional triamcinolone injection. The size of the lesion was measured serially every week during the first month, every 2 weeks for the second month, and then monthly for another 2 months. The refractive error and degree of ptosis if present were measured before injection and at the end of the study.Results: There was reduction in the size of hemangioma, astigmatic error, and degree of ptosis in both groups. The difference in outcome between both groups was not statistically significant. Rebound growth occurred in 25% of the propranolol group and 30% of the steroid group but responded to reinjection. No adverse effects were reported during or after intralesional propranolol injection.Conclusion: Intralesional propranolol injection is an alternative and effective method for treatment of infantile periocular hemangioma.Keywords: propranolol, intralesional, periocular capillary hemangioma
format article
author Awadein A
Fakhry MA
author_facet Awadein A
Fakhry MA
author_sort Awadein A
title Evaluation of intralesional propranolol for periocular capillary hemangioma
title_short Evaluation of intralesional propranolol for periocular capillary hemangioma
title_full Evaluation of intralesional propranolol for periocular capillary hemangioma
title_fullStr Evaluation of intralesional propranolol for periocular capillary hemangioma
title_full_unstemmed Evaluation of intralesional propranolol for periocular capillary hemangioma
title_sort evaluation of intralesional propranolol for periocular capillary hemangioma
publisher Dove Medical Press
publishDate 2011
url https://doaj.org/article/1b20246580db44068a0936dc11dba58d
work_keys_str_mv AT awadeina evaluationofintralesionalpropranololforperiocularcapillaryhemangioma
AT fakhryma evaluationofintralesionalpropranololforperiocularcapillaryhemangioma
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