Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex

Differential roles of ARID1B in excitatory and inhibitory neural progenitors in the developing cortex

Abstract Genetic evidence indicates that haploinsufficiency of ARID1B causes intellectual disability (ID) and autism spectrum disorder (ASD), but the neural function of ARID1B is largely unknown. Using both conditional and global Arid1b knockout mouse strains, we examined the role of ARID1B in neura...

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Autores principales: Jeffrey J. Moffat, Eui-Man Jung, Minhan Ka, Byeong Tak Jeon, Hyunkyoung Lee, Woo-Yang Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/1b26474e510c494a973e8f34bf106e31
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