The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation.

The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation.

The etiology of radiation-induced cardiovascular disease (CVD) after chronic exposure to low doses of ionizing radiation is only marginally understood. We have previously shown that a chronic low-dose rate exposure (4.1 mGy/h) causes human umbilical vein endothelial cells (HUVECs) to prematurely sen...

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Autores principales: Ramesh Yentrapalli, Omid Azimzadeh, Arundhathi Sriharshan, Katharina Malinowsky, Juliane Merl, Andrzej Wojcik, Mats Harms-Ringdahl, Michael J Atkinson, Karl-Friedrich Becker, Siamak Haghdoost, Soile Tapio
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1b2dff6adb4d485785411ec1693318d6
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