ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
Multivesicular bodies (MVB) are endosomal compartments that can either fuse with the plasma membrane for the secretion of exosomes, or fuse with the lysosome and be degraded along with their contents. Here, the authors show that ISGylation of the MVB protein TSG101 impairs exosome secretion and acts...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2016
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/1b2e7f717e724460ac0843fd8652dd65 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|