Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update

DL Waters1, RN Baumgartner2, PJ Garry3, B Vellas41Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; 2Department of Epidemiology and Population Health, University of Louisville, Louisville, Kentucky, USA; 3Department of Pathology, Uni...

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Autores principales: DL Waters, RN Baumgartner, PJ Garry, et al.
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Publicado: Dove Medical Press 2010
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spelling oai:doaj.org-article:1b32a03a644846a890404d39f61a6c872021-12-02T06:39:16ZAdvantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update1178-1998https://doaj.org/article/1b32a03a644846a890404d39f61a6c872010-09-01T00:00:00Zhttps://www.dovepress.com/advantages-of-dietary-exercise-related-and-therapeutic-interventions-t-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998DL Waters1, RN Baumgartner2, PJ Garry3, B Vellas41Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; 2Department of Epidemiology and Population Health, University of Louisville, Louisville, Kentucky, USA; 3Department of Pathology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA; 4Department of Internal Medicine and Geriatric Medicine, University Hospital Center of Toulouse, Gerontopole, Toulouse, FranceAbstract: Sarcopenia is the loss of skeletal muscle mass and function with aging. Although the term sarcopenia was first coined in 1989, its etiology is still poorly understood. Moreover, a consensus for defining sarcopenia continues to elude us. Sarcopenic changes in the muscle include losses in muscle fiber quantity and quality, alpha-motor neurons, protein synthesis rates, and anabolic and sex hormone production. Other factors include basal metabolic rate, increased protein dietary requirements, and chronic inflammation secondary to age-related changes in cytokines and oxidative stress. These changes lead to decreased overall physical functioning, increased frailty, falls risk, and ultimately the loss of independent living. Because the intertwining relationships of these factors are complex, effective treatment options are still under investigation. The published data on sarcopenia are vast, and this review is not intended to be exhaustive. The aim of this review is to provide an update on the current knowledge of the definition, etiology, consequences, and current clinical trials that may help address this pressing public health problem for our aging populations.Keywords: aging, muscle loss, nutrition, physical activityDL WatersRN BaumgartnerPJ Garryet al.Dove Medical PressarticlesarcopenianutritionexerciseinterventionsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 5, Pp 259-270 (2010)
institution DOAJ
collection DOAJ
language EN
topic sarcopenia
nutrition
exercise
interventions
Geriatrics
RC952-954.6
spellingShingle sarcopenia
nutrition
exercise
interventions
Geriatrics
RC952-954.6
DL Waters
RN Baumgartner
PJ Garry
et al.
Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
description DL Waters1, RN Baumgartner2, PJ Garry3, B Vellas41Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; 2Department of Epidemiology and Population Health, University of Louisville, Louisville, Kentucky, USA; 3Department of Pathology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA; 4Department of Internal Medicine and Geriatric Medicine, University Hospital Center of Toulouse, Gerontopole, Toulouse, FranceAbstract: Sarcopenia is the loss of skeletal muscle mass and function with aging. Although the term sarcopenia was first coined in 1989, its etiology is still poorly understood. Moreover, a consensus for defining sarcopenia continues to elude us. Sarcopenic changes in the muscle include losses in muscle fiber quantity and quality, alpha-motor neurons, protein synthesis rates, and anabolic and sex hormone production. Other factors include basal metabolic rate, increased protein dietary requirements, and chronic inflammation secondary to age-related changes in cytokines and oxidative stress. These changes lead to decreased overall physical functioning, increased frailty, falls risk, and ultimately the loss of independent living. Because the intertwining relationships of these factors are complex, effective treatment options are still under investigation. The published data on sarcopenia are vast, and this review is not intended to be exhaustive. The aim of this review is to provide an update on the current knowledge of the definition, etiology, consequences, and current clinical trials that may help address this pressing public health problem for our aging populations.Keywords: aging, muscle loss, nutrition, physical activity
format article
author DL Waters
RN Baumgartner
PJ Garry
et al.
author_facet DL Waters
RN Baumgartner
PJ Garry
et al.
author_sort DL Waters
title Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
title_short Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
title_full Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
title_fullStr Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
title_full_unstemmed Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
title_sort advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update
publisher Dove Medical Press
publishDate 2010
url https://doaj.org/article/1b32a03a644846a890404d39f61a6c87
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