A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor.

A paradoxical method to enhance compensatory lung growth: Utilizing a VEGF inhibitor.

Exogenous vascular endothelial growth factor (VEGF) accelerates compensatory lung growth (CLG) in mice after unilateral pneumonectomy. In this study, we unexpectedly discovered a method to enhance CLG with a VEGF inhibitor, soluble VEGFR1. Eight-week-old C57BL/6 male mice underwent left pneumonectom...

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Bibliographic Details
Main Authors: Duy T Dao, Lorenzo Anez-Bustillos, Sahir S Jabbouri, Amy Pan, Hiroko Kishikawa, Paul D Mitchell, Gillian L Fell, Meredith A Baker, Randolph S Watnick, Hong Chen, Michael S Rogers, Diane R Bielenberg, Mark Puder
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2018
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/1b3d0cc9fe344dfcb85c9aed00b3e2fd
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