Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor

Piero Mannu1, Salvatore Rinaldi1,2, Vania Fontani1, Alessandro Castagna11Rinaldi-Fontani Institute, Department of Neuro-Psycho-Physio Pathology, Florence, Italy; 2School of Occupational Medicine, University of Florence, Florence, ItalyBackground: The bipolar spectrum disorders are considered an impo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mannu P, Rinaldi S, Fontani V, Castagna A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/1b3fba9192844250b6fa21b64dcd037d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1b3fba9192844250b6fa21b64dcd037d
record_format	dspace
spelling	oai:doaj.org-article:1b3fba9192844250b6fa21b64dcd037d2021-12-02T05:55:32ZLong-term treatment of bipolar disorder with a radioelectric asymmetric conveyor1176-63281178-2021https://doaj.org/article/1b3fba9192844250b6fa21b64dcd037d2011-06-01T00:00:00Zhttp://www.dovepress.com/long-term-treatment-of-bipolar-disorder-with-a-radioelectric-asymmetri-a7662https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Piero Mannu1, Salvatore Rinaldi1,2, Vania Fontani1, Alessandro Castagna11Rinaldi-Fontani Institute, Department of Neuro-Psycho-Physio Pathology, Florence, Italy; 2School of Occupational Medicine, University of Florence, Florence, ItalyBackground: The bipolar spectrum disorders are considered an important and frequent psychiatric problem. The clinical complexity of these illnesses due to the coexistence of depressive and excitative phases is correlated with the global difficulty of adequate treatment; consequently, the prognosis is not optimal. For this reason, in recent years, novel nonpharmacologic physical approaches have been tested for bipolar disorders, with encouraging results. The aim of this study was to evaluate the long-term effectiveness of a radioelectric asymmetric brain stimulation device associated with lithium (REAC-lithium) versus previous treatments in subjects with bipolar disorder I or II, evaluated as the number of recurrences compared with the period of illness preceding treatment with REAC-lithium.Methods: The charts of 56 bipolar patients attending our institute were retrospectively evaluated. Treatment with REAC-lithium was administered following the standard Rinaldi-Fontani Institute protocol. Add-on treatments were allowed in the event of manic or depressive recurrence. Eight patients (Group 1) were followed for 30.2 &plusmn; 3.0 months, 14 patients (Group 2) were followed for 25.3 &plusmn; 3.3 months, 25 patients (Group 3) were followed for 20.3 &plusmn; 1.6 months, and nine patients (Group 4) were followed for 16.2 &plusmn; 0.5 months.Results: After REAC-lithium treatment, the number of manic and depressive episodes in Group 1 decreased from 2.1 &plusmn; 0.6 and 3.0 &plusmn; 0.7 to 0.12 &plusmn; 0.0 and 0.8 &plusmn; 0.4, respectively. In Group 2, the number of manic and depressive episodes decreased from 2.4 &plusmn; 0.6 and 3.9 &plusmn; 0.7 to 0.14 &plusmn; 0.2 and 0.0 &plusmn; 0.0, respectively. In Group 3, the number of manic and depressive episodes decreased from 2.6 &plusmn; 0.8 and 3.6 &plusmn; 0.9 to 0.04 &plusmn; 0.0 and 0.0 &plusmn; 0.0, respectively. In Group 4, the number of manic and depressive episodes decreased from 2.6 &plusmn; 1.1 and 3.7 &plusmn; 1.0 to 0.1 &plusmn; 0.0 and 0.0 &plusmn; 0.0, respectively. All results were statistically significant.Conclusion: REAC showed good efficacy in treating both the manic and depressive phases of bipolar disorder, and in the prevention of recurrences/relapses.Keywords: bipolar disorder, stress, radioelectric asymmetric brain stimulationMannu PRinaldi SFontani VCastagna ADove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Issue 1, Pp 373-379 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Mannu P Rinaldi S Fontani V Castagna A Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
description	Piero Mannu1, Salvatore Rinaldi1,2, Vania Fontani1, Alessandro Castagna11Rinaldi-Fontani Institute, Department of Neuro-Psycho-Physio Pathology, Florence, Italy; 2School of Occupational Medicine, University of Florence, Florence, ItalyBackground: The bipolar spectrum disorders are considered an important and frequent psychiatric problem. The clinical complexity of these illnesses due to the coexistence of depressive and excitative phases is correlated with the global difficulty of adequate treatment; consequently, the prognosis is not optimal. For this reason, in recent years, novel nonpharmacologic physical approaches have been tested for bipolar disorders, with encouraging results. The aim of this study was to evaluate the long-term effectiveness of a radioelectric asymmetric brain stimulation device associated with lithium (REAC-lithium) versus previous treatments in subjects with bipolar disorder I or II, evaluated as the number of recurrences compared with the period of illness preceding treatment with REAC-lithium.Methods: The charts of 56 bipolar patients attending our institute were retrospectively evaluated. Treatment with REAC-lithium was administered following the standard Rinaldi-Fontani Institute protocol. Add-on treatments were allowed in the event of manic or depressive recurrence. Eight patients (Group 1) were followed for 30.2 &plusmn; 3.0 months, 14 patients (Group 2) were followed for 25.3 &plusmn; 3.3 months, 25 patients (Group 3) were followed for 20.3 &plusmn; 1.6 months, and nine patients (Group 4) were followed for 16.2 &plusmn; 0.5 months.Results: After REAC-lithium treatment, the number of manic and depressive episodes in Group 1 decreased from 2.1 &plusmn; 0.6 and 3.0 &plusmn; 0.7 to 0.12 &plusmn; 0.0 and 0.8 &plusmn; 0.4, respectively. In Group 2, the number of manic and depressive episodes decreased from 2.4 &plusmn; 0.6 and 3.9 &plusmn; 0.7 to 0.14 &plusmn; 0.2 and 0.0 &plusmn; 0.0, respectively. In Group 3, the number of manic and depressive episodes decreased from 2.6 &plusmn; 0.8 and 3.6 &plusmn; 0.9 to 0.04 &plusmn; 0.0 and 0.0 &plusmn; 0.0, respectively. In Group 4, the number of manic and depressive episodes decreased from 2.6 &plusmn; 1.1 and 3.7 &plusmn; 1.0 to 0.1 &plusmn; 0.0 and 0.0 &plusmn; 0.0, respectively. All results were statistically significant.Conclusion: REAC showed good efficacy in treating both the manic and depressive phases of bipolar disorder, and in the prevention of recurrences/relapses.Keywords: bipolar disorder, stress, radioelectric asymmetric brain stimulation
format	article
author	Mannu P Rinaldi S Fontani V Castagna A
author_facet	Mannu P Rinaldi S Fontani V Castagna A
author_sort	Mannu P
title	Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
title_short	Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
title_full	Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
title_fullStr	Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
title_full_unstemmed	Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
title_sort	long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/1b3fba9192844250b6fa21b64dcd037d
work_keys_str_mv	AT mannup longtermtreatmentofbipolardisorderwitharadioelectricasymmetricconveyor AT rinaldis longtermtreatmentofbipolardisorderwitharadioelectricasymmetricconveyor AT fontaniv longtermtreatmentofbipolardisorderwitharadioelectricasymmetricconveyor AT castagnaa longtermtreatmentofbipolardisorderwitharadioelectricasymmetricconveyor
_version_	1718400156498395136

Long-term treatment of bipolar disorder with a radioelectric asymmetric conveyor

Ejemplares similares