HATRIC-based identification of receptors for orphan ligands

Technologies for identifying receptor-ligand pairs on living cells at physiological conditions remain scarce. Here, the authors develop a mass spectrometry-based ligand receptor capture technology that can identify receptors for a diverse range of ligands at physiological pH with as few as a million...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nadine Sobotzki, Michael A. Schafroth, Alina Rudnicka, Anika Koetemann, Florian Marty, Sandra Goetze, Yohei Yamauchi, Erick M. Carreira, Bernd Wollscheid
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1b3ff8e59603407da4c0f41e48155ad3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1b3ff8e59603407da4c0f41e48155ad3
record_format	dspace
spelling	oai:doaj.org-article:1b3ff8e59603407da4c0f41e48155ad32021-12-02T15:33:38ZHATRIC-based identification of receptors for orphan ligands10.1038/s41467-018-03936-z2041-1723https://doaj.org/article/1b3ff8e59603407da4c0f41e48155ad32018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03936-zhttps://doaj.org/toc/2041-1723Technologies for identifying receptor-ligand pairs on living cells at physiological conditions remain scarce. Here, the authors develop a mass spectrometry-based ligand receptor capture technology that can identify receptors for a diverse range of ligands at physiological pH with as few as a million cells.Nadine SobotzkiMichael A. SchafrothAlina RudnickaAnika KoetemannFlorian MartySandra GoetzeYohei YamauchiErick M. CarreiraBernd WollscheidNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nadine Sobotzki Michael A. Schafroth Alina Rudnicka Anika Koetemann Florian Marty Sandra Goetze Yohei Yamauchi Erick M. Carreira Bernd Wollscheid HATRIC-based identification of receptors for orphan ligands
description	Technologies for identifying receptor-ligand pairs on living cells at physiological conditions remain scarce. Here, the authors develop a mass spectrometry-based ligand receptor capture technology that can identify receptors for a diverse range of ligands at physiological pH with as few as a million cells.
format	article
author	Nadine Sobotzki Michael A. Schafroth Alina Rudnicka Anika Koetemann Florian Marty Sandra Goetze Yohei Yamauchi Erick M. Carreira Bernd Wollscheid
author_facet	Nadine Sobotzki Michael A. Schafroth Alina Rudnicka Anika Koetemann Florian Marty Sandra Goetze Yohei Yamauchi Erick M. Carreira Bernd Wollscheid
author_sort	Nadine Sobotzki
title	HATRIC-based identification of receptors for orphan ligands
title_short	HATRIC-based identification of receptors for orphan ligands
title_full	HATRIC-based identification of receptors for orphan ligands
title_fullStr	HATRIC-based identification of receptors for orphan ligands
title_full_unstemmed	HATRIC-based identification of receptors for orphan ligands
title_sort	hatric-based identification of receptors for orphan ligands
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/1b3ff8e59603407da4c0f41e48155ad3
work_keys_str_mv	AT nadinesobotzki hatricbasedidentificationofreceptorsfororphanligands AT michaelaschafroth hatricbasedidentificationofreceptorsfororphanligands AT alinarudnicka hatricbasedidentificationofreceptorsfororphanligands AT anikakoetemann hatricbasedidentificationofreceptorsfororphanligands AT florianmarty hatricbasedidentificationofreceptorsfororphanligands AT sandragoetze hatricbasedidentificationofreceptorsfororphanligands AT yoheiyamauchi hatricbasedidentificationofreceptorsfororphanligands AT erickmcarreira hatricbasedidentificationofreceptorsfororphanligands AT berndwollscheid hatricbasedidentificationofreceptorsfororphanligands
_version_	1718387067761721344

HATRIC-based identification of receptors for orphan ligands

Ejemplares similares