Efficacy, safety and tolerability of drugs studied in phase 3 randomized controlled trials in solid tumors over the last decade

Abstract Data suggest that for newly approved cancer drugs safety and tolerability are worse than in control arms of registration trials. Less is known about the balance between efficacy and toxicity of drugs studied in unselected phase 3 randomized controlled trials (RCTs) including those not resul...

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Autores principales: Domen Ribnikar, Hadar Goldvaser, Zachary W. Veitch, Alberto Ocana, Arnoud J. Templeton, Boštjan Šeruga, Eitan Amir
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1b46992acee94202aa4a2afa74817e81
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