APC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencing.

APC/C-mediated degradation of dsRNA-binding protein 4 (DRB4) involved in RNA silencing.

<h4>Background</h4>Selective protein degradation via the ubiquitin-26S proteasome is a major mechanism underlying DNA replication and cell division in all Eukaryotes. In particular, the APC/C (Anaphase Promoting Complex or Cyclosome) is a master ubiquitin protein ligase (E3) that targets...

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Autores principales: Katia Marrocco, Marie-Claire Criqui, Jérôme Zervudacki, Gregory Schott, Herfried Eisler, Aude Parnet, Patrice Dunoyer, Pascal Genschik
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1b6eb417dd9f4bcbbd7018e5882cae3f
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