Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management

Psoriasis is a chronic inflammatory autoimmune disorder that moderately affects social and interpersonal relationships. Conventional treatments for psoriasis have certain problems, such as poor drug penetration through the skin, hyper-pigmentation, and a burning sensation on normal and diseased skin...

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Autores principales:	Sukhbir Singh, Neelam Sharma, Tapan Behl, Bidhan Chandra Sarkar, Hasi Rani Saha, Kanika Garg, Supriya Kamari Singh, Sandeep Arora, Md. Shah Amran, Ahmed A. H. Abdellatif, Anwar L. Bilgrami, Ghulam Md Ashraf, Md. Sohanur Rahman
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	colloidal drug delivery system dendrimers liposome microemulsion nano-structured lipid carrier psoriasis Pharmacy and materia medica RS1-441
Acceso en línea:	https://doaj.org/article/1b76b652a3b04a6388ac8040735a9b07
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spelling	oai:doaj.org-article:1b76b652a3b04a6388ac8040735a9b072021-11-25T18:42:43ZPromising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management10.3390/pharmaceutics131119781999-4923https://doaj.org/article/1b76b652a3b04a6388ac8040735a9b072021-11-01T00:00:00Zhttps://www.mdpi.com/1999-4923/13/11/1978https://doaj.org/toc/1999-4923Psoriasis is a chronic inflammatory autoimmune disorder that moderately affects social and interpersonal relationships. Conventional treatments for psoriasis have certain problems, such as poor drug penetration through the skin, hyper-pigmentation, and a burning sensation on normal and diseased skin. Colloidal drug delivery systems overcome the pitfalls of conventional approaches for psoriasis therapeutics and have improved patient safety parameters, compliance, and superior effectiveness. They also entail reduced toxicity. This comprehensive review’s topics include the pathogenesis of psoriasis, causes and types of psoriasis, conventional treatment alternatives for psoriasis, the need for colloidal drug delivery systems, and recent studies in colloidal drug delivery systems for the treatment of psoriasis. This review briefly describes colloidal drug delivery approaches, such as emulsion systems—i.e., multiple emulsion, microemulsion, and nano-emulsion; vesicular systems—i.e., liposomes, ethosomes, noisomes, and transferosomes; and particulate systems—i.e., solid lipid nanoparticles, solid lipid microparticles, nano-structured lipid carriers, dendrimers, nanocrystals, polymeric nanoparticles, and gold nanoparticles. The review was compiled through an extensive search of the literature through the PubMed, Google Scholar, and ScienceDirect databases. A survey of literature revealed seven formulations based upon emulsion systems, six vesicular drug delivery systems, and fourteen particulate systems reported for antipsoriatic drugs. Based on the literature studies of colloidal approaches for psoriasis management carried out in recent years, it has been concluded that colloidal pharmaceutical formulations could be investigated broadly and have a broad scope for effective management of many skin disorders in the coming decades.Sukhbir SinghNeelam SharmaTapan BehlBidhan Chandra SarkarHasi Rani SahaKanika GargSupriya Kamari SinghSandeep AroraMd. Shah AmranAhmed A. H. AbdellatifAnwar L. BilgramiGhulam Md AshrafMd. Sohanur RahmanMDPI AGarticlecolloidal drug delivery systemdendrimersliposomemicroemulsionnano-structured lipid carrierpsoriasisPharmacy and materia medicaRS1-441ENPharmaceutics, Vol 13, Iss 1978, p 1978 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	colloidal drug delivery system dendrimers liposome microemulsion nano-structured lipid carrier psoriasis Pharmacy and materia medica RS1-441
spellingShingle	colloidal drug delivery system dendrimers liposome microemulsion nano-structured lipid carrier psoriasis Pharmacy and materia medica RS1-441 Sukhbir Singh Neelam Sharma Tapan Behl Bidhan Chandra Sarkar Hasi Rani Saha Kanika Garg Supriya Kamari Singh Sandeep Arora Md. Shah Amran Ahmed A. H. Abdellatif Anwar L. Bilgrami Ghulam Md Ashraf Md. Sohanur Rahman Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
description	Psoriasis is a chronic inflammatory autoimmune disorder that moderately affects social and interpersonal relationships. Conventional treatments for psoriasis have certain problems, such as poor drug penetration through the skin, hyper-pigmentation, and a burning sensation on normal and diseased skin. Colloidal drug delivery systems overcome the pitfalls of conventional approaches for psoriasis therapeutics and have improved patient safety parameters, compliance, and superior effectiveness. They also entail reduced toxicity. This comprehensive review’s topics include the pathogenesis of psoriasis, causes and types of psoriasis, conventional treatment alternatives for psoriasis, the need for colloidal drug delivery systems, and recent studies in colloidal drug delivery systems for the treatment of psoriasis. This review briefly describes colloidal drug delivery approaches, such as emulsion systems—i.e., multiple emulsion, microemulsion, and nano-emulsion; vesicular systems—i.e., liposomes, ethosomes, noisomes, and transferosomes; and particulate systems—i.e., solid lipid nanoparticles, solid lipid microparticles, nano-structured lipid carriers, dendrimers, nanocrystals, polymeric nanoparticles, and gold nanoparticles. The review was compiled through an extensive search of the literature through the PubMed, Google Scholar, and ScienceDirect databases. A survey of literature revealed seven formulations based upon emulsion systems, six vesicular drug delivery systems, and fourteen particulate systems reported for antipsoriatic drugs. Based on the literature studies of colloidal approaches for psoriasis management carried out in recent years, it has been concluded that colloidal pharmaceutical formulations could be investigated broadly and have a broad scope for effective management of many skin disorders in the coming decades.
format	article
author	Sukhbir Singh Neelam Sharma Tapan Behl Bidhan Chandra Sarkar Hasi Rani Saha Kanika Garg Supriya Kamari Singh Sandeep Arora Md. Shah Amran Ahmed A. H. Abdellatif Anwar L. Bilgrami Ghulam Md Ashraf Md. Sohanur Rahman
author_facet	Sukhbir Singh Neelam Sharma Tapan Behl Bidhan Chandra Sarkar Hasi Rani Saha Kanika Garg Supriya Kamari Singh Sandeep Arora Md. Shah Amran Ahmed A. H. Abdellatif Anwar L. Bilgrami Ghulam Md Ashraf Md. Sohanur Rahman
author_sort	Sukhbir Singh
title	Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
title_short	Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
title_full	Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
title_fullStr	Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
title_full_unstemmed	Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management
title_sort	promising strategies of colloidal drug delivery-based approaches in psoriasis management
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/1b76b652a3b04a6388ac8040735a9b07
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Promising Strategies of Colloidal Drug Delivery-Based Approaches in Psoriasis Management

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