The controversy over the association between statins use and progression of age-related macular degeneration: a mini review

Vasileios Peponis1, Spyridon E Chalkiadakis1, Stefanos Bonovas2,3, Nikolaos M Sitaras21Athens Eye Hospital, 2nd Eye Clinic, Athens, Greece; 2Department of Pharmacology, School of Medicine, University of Athens, Greece; 3Center for Diseases Control and Prevention, Athens, GreeceObjective: Age-related...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vasileios Peponis, Spyridon E Chalkiadakis, Stefanos Bonovas, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/1b78bc78f9434ff899ed9e35f413b310
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1b78bc78f9434ff899ed9e35f413b310
record_format	dspace
spelling	oai:doaj.org-article:1b78bc78f9434ff899ed9e35f413b3102021-12-02T04:44:58ZThe controversy over the association between statins use and progression of age-related macular degeneration: a mini review1177-54671177-5483https://doaj.org/article/1b78bc78f9434ff899ed9e35f413b3102010-07-01T00:00:00Zhttp://www.dovepress.com/the-controversy-over-the-association-between-statins-use-and-progressi-a4941https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Vasileios Peponis1, Spyridon E Chalkiadakis1, Stefanos Bonovas2,3, Nikolaos M Sitaras21Athens Eye Hospital, 2nd Eye Clinic, Athens, Greece; 2Department of Pharmacology, School of Medicine, University of Athens, Greece; 3Center for Diseases Control and Prevention, Athens, GreeceObjective: Age-related macular degeneration (AMD) is the leading cause of blindness in &not;western societies. Statins comprise a class of pharmacological agents that reduce plasma cholesterol levels, and have been shown to prevent progression of atherosclerosis and reduce cardiovascular mortality. The relationship between these medications and AMD has been evaluated in several recent studies. Herein, we examine the current evidence for an association between statin use and risk of AMD.Methods: Literature database search (Medline, Scopus, and Science Citation Index Expanded) for articles published up to March 2010, using particular search terms.Results: From the current evidence available, it is not safe to conclude upon the assumption of a protective effect of statins against age-related maculopathy and AMD.Conclusion: There is a need for large scale prospective studies with a long follow-up period and accurate assessment of AMD to further explore this matter.Keywords: age-related macular degeneration (AMD), blindness, statin use, controversy Vasileios PeponisSpyridon E ChalkiadakisStefanos Bonovaset alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 865-869 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Vasileios Peponis Spyridon E Chalkiadakis Stefanos Bonovas et al The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
description	Vasileios Peponis1, Spyridon E Chalkiadakis1, Stefanos Bonovas2,3, Nikolaos M Sitaras21Athens Eye Hospital, 2nd Eye Clinic, Athens, Greece; 2Department of Pharmacology, School of Medicine, University of Athens, Greece; 3Center for Diseases Control and Prevention, Athens, GreeceObjective: Age-related macular degeneration (AMD) is the leading cause of blindness in &not;western societies. Statins comprise a class of pharmacological agents that reduce plasma cholesterol levels, and have been shown to prevent progression of atherosclerosis and reduce cardiovascular mortality. The relationship between these medications and AMD has been evaluated in several recent studies. Herein, we examine the current evidence for an association between statin use and risk of AMD.Methods: Literature database search (Medline, Scopus, and Science Citation Index Expanded) for articles published up to March 2010, using particular search terms.Results: From the current evidence available, it is not safe to conclude upon the assumption of a protective effect of statins against age-related maculopathy and AMD.Conclusion: There is a need for large scale prospective studies with a long follow-up period and accurate assessment of AMD to further explore this matter.Keywords: age-related macular degeneration (AMD), blindness, statin use, controversy
format	article
author	Vasileios Peponis Spyridon E Chalkiadakis Stefanos Bonovas et al
author_facet	Vasileios Peponis Spyridon E Chalkiadakis Stefanos Bonovas et al
author_sort	Vasileios Peponis
title	The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
title_short	The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
title_full	The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
title_fullStr	The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
title_full_unstemmed	The controversy over the association between statins use and progression of age-related macular degeneration: a mini review
title_sort	controversy over the association between statins use and progression of age-related macular degeneration: a mini review
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/1b78bc78f9434ff899ed9e35f413b310
work_keys_str_mv	AT vasileiospeponis thecontroversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT spyridonechalkiadakis thecontroversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT stefanosbonovas thecontroversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT etal thecontroversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT vasileiospeponis controversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT spyridonechalkiadakis controversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT stefanosbonovas controversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview AT etal controversyovertheassociationbetweenstatinsuseandprogressionofagerelatedmaculardegenerationaminireview
_version_	1718401078832136192

The controversy over the association between statins use and progression of age-related macular degeneration: a mini review

Ejemplares similares