Genetic mapping of cell type specificity for complex traits

Tissue- and cell type-specific information helps to interpret findings from genome-wide association studies. Here, the authors leverage multiple single cell expression datasets to infer cell type specificity of traits.

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Autores principales:	Kyoko Watanabe, Maša Umićević Mirkov, Christiaan A. de Leeuw, Martijn P. van den Heuvel, Danielle Posthuma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1b79e2c2d7734c8abaf4baac708ba480
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spelling	oai:doaj.org-article:1b79e2c2d7734c8abaf4baac708ba4802021-12-02T15:36:22ZGenetic mapping of cell type specificity for complex traits10.1038/s41467-019-11181-12041-1723https://doaj.org/article/1b79e2c2d7734c8abaf4baac708ba4802019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11181-1https://doaj.org/toc/2041-1723Tissue- and cell type-specific information helps to interpret findings from genome-wide association studies. Here, the authors leverage multiple single cell expression datasets to infer cell type specificity of traits.Kyoko WatanabeMaša Umićević MirkovChristiaan A. de LeeuwMartijn P. van den HeuvelDanielle PosthumaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kyoko Watanabe Maša Umićević Mirkov Christiaan A. de Leeuw Martijn P. van den Heuvel Danielle Posthuma Genetic mapping of cell type specificity for complex traits
description	Tissue- and cell type-specific information helps to interpret findings from genome-wide association studies. Here, the authors leverage multiple single cell expression datasets to infer cell type specificity of traits.
format	article
author	Kyoko Watanabe Maša Umićević Mirkov Christiaan A. de Leeuw Martijn P. van den Heuvel Danielle Posthuma
author_facet	Kyoko Watanabe Maša Umićević Mirkov Christiaan A. de Leeuw Martijn P. van den Heuvel Danielle Posthuma
author_sort	Kyoko Watanabe
title	Genetic mapping of cell type specificity for complex traits
title_short	Genetic mapping of cell type specificity for complex traits
title_full	Genetic mapping of cell type specificity for complex traits
title_fullStr	Genetic mapping of cell type specificity for complex traits
title_full_unstemmed	Genetic mapping of cell type specificity for complex traits
title_sort	genetic mapping of cell type specificity for complex traits
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1b79e2c2d7734c8abaf4baac708ba480
work_keys_str_mv	AT kyokowatanabe geneticmappingofcelltypespecificityforcomplextraits AT masaumicevicmirkov geneticmappingofcelltypespecificityforcomplextraits AT christiaanadeleeuw geneticmappingofcelltypespecificityforcomplextraits AT martijnpvandenheuvel geneticmappingofcelltypespecificityforcomplextraits AT danielleposthuma geneticmappingofcelltypespecificityforcomplextraits
_version_	1718386277067259904

Genetic mapping of cell type specificity for complex traits

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