Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

Oral cancer has region-specific histopathological and molecular characteristics, complicating its classification by the standard tumor-node-metastasis system. Here, the authors combine discovery and targeted proteomics with IHC to identify region-specific and saliva biomarkers for oral cancer progno...

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Autores principales: Carolina Moretto Carnielli, Carolina Carneiro Soares Macedo, Tatiane De Rossi, Daniela Campos Granato, César Rivera, Romênia Ramos Domingues, Bianca Alves Pauletti, Sami Yokoo, Henry Heberle, Ariane Fidelis Busso-Lopes, Nilva Karla Cervigne, Iris Sawazaki-Calone, Gabriela Vaz Meirelles, Fábio Albuquerque Marchi, Guilherme Pimentel Telles, Rosane Minghim, Ana Carolina Prado Ribeiro, Thaís Bianca Brandão, Gilberto de Castro, Wilfredo Alejandro González-Arriagada, Alexandre Gomes, Fabio Penteado, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Priscila Campioni Rodrigues, Elias Sundquist, Tuula Salo, Sabrina Daniela da Silva, Moulay A. Alaoui-Jamali, Edgard Graner, Jay W. Fox, Ricardo Della Coletta, Adriana Franco Paes Leme
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1b7cd93db80e4a69b02dbb19996d562c
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spelling oai:doaj.org-article:1b7cd93db80e4a69b02dbb19996d562c2021-12-02T15:34:49ZCombining discovery and targeted proteomics reveals a prognostic signature in oral cancer10.1038/s41467-018-05696-22041-1723https://doaj.org/article/1b7cd93db80e4a69b02dbb19996d562c2018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05696-2https://doaj.org/toc/2041-1723Oral cancer has region-specific histopathological and molecular characteristics, complicating its classification by the standard tumor-node-metastasis system. Here, the authors combine discovery and targeted proteomics with IHC to identify region-specific and saliva biomarkers for oral cancer prognosis.Carolina Moretto CarnielliCarolina Carneiro Soares MacedoTatiane De RossiDaniela Campos GranatoCésar RiveraRomênia Ramos DominguesBianca Alves PaulettiSami YokooHenry HeberleAriane Fidelis Busso-LopesNilva Karla CervigneIris Sawazaki-CaloneGabriela Vaz MeirellesFábio Albuquerque MarchiGuilherme Pimentel TellesRosane MinghimAna Carolina Prado RibeiroThaís Bianca BrandãoGilberto de CastroWilfredo Alejandro González-ArriagadaAlexandre GomesFabio PenteadoAlan Roger Santos-SilvaMárcio Ajudarte LopesPriscila Campioni RodriguesElias SundquistTuula SaloSabrina Daniela da SilvaMoulay A. Alaoui-JamaliEdgard GranerJay W. FoxRicardo Della ColettaAdriana Franco Paes LemeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Carolina Moretto Carnielli
Carolina Carneiro Soares Macedo
Tatiane De Rossi
Daniela Campos Granato
César Rivera
Romênia Ramos Domingues
Bianca Alves Pauletti
Sami Yokoo
Henry Heberle
Ariane Fidelis Busso-Lopes
Nilva Karla Cervigne
Iris Sawazaki-Calone
Gabriela Vaz Meirelles
Fábio Albuquerque Marchi
Guilherme Pimentel Telles
Rosane Minghim
Ana Carolina Prado Ribeiro
Thaís Bianca Brandão
Gilberto de Castro
Wilfredo Alejandro González-Arriagada
Alexandre Gomes
Fabio Penteado
Alan Roger Santos-Silva
Márcio Ajudarte Lopes
Priscila Campioni Rodrigues
Elias Sundquist
Tuula Salo
Sabrina Daniela da Silva
Moulay A. Alaoui-Jamali
Edgard Graner
Jay W. Fox
Ricardo Della Coletta
Adriana Franco Paes Leme
Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
description Oral cancer has region-specific histopathological and molecular characteristics, complicating its classification by the standard tumor-node-metastasis system. Here, the authors combine discovery and targeted proteomics with IHC to identify region-specific and saliva biomarkers for oral cancer prognosis.
format article
author Carolina Moretto Carnielli
Carolina Carneiro Soares Macedo
Tatiane De Rossi
Daniela Campos Granato
César Rivera
Romênia Ramos Domingues
Bianca Alves Pauletti
Sami Yokoo
Henry Heberle
Ariane Fidelis Busso-Lopes
Nilva Karla Cervigne
Iris Sawazaki-Calone
Gabriela Vaz Meirelles
Fábio Albuquerque Marchi
Guilherme Pimentel Telles
Rosane Minghim
Ana Carolina Prado Ribeiro
Thaís Bianca Brandão
Gilberto de Castro
Wilfredo Alejandro González-Arriagada
Alexandre Gomes
Fabio Penteado
Alan Roger Santos-Silva
Márcio Ajudarte Lopes
Priscila Campioni Rodrigues
Elias Sundquist
Tuula Salo
Sabrina Daniela da Silva
Moulay A. Alaoui-Jamali
Edgard Graner
Jay W. Fox
Ricardo Della Coletta
Adriana Franco Paes Leme
author_facet Carolina Moretto Carnielli
Carolina Carneiro Soares Macedo
Tatiane De Rossi
Daniela Campos Granato
César Rivera
Romênia Ramos Domingues
Bianca Alves Pauletti
Sami Yokoo
Henry Heberle
Ariane Fidelis Busso-Lopes
Nilva Karla Cervigne
Iris Sawazaki-Calone
Gabriela Vaz Meirelles
Fábio Albuquerque Marchi
Guilherme Pimentel Telles
Rosane Minghim
Ana Carolina Prado Ribeiro
Thaís Bianca Brandão
Gilberto de Castro
Wilfredo Alejandro González-Arriagada
Alexandre Gomes
Fabio Penteado
Alan Roger Santos-Silva
Márcio Ajudarte Lopes
Priscila Campioni Rodrigues
Elias Sundquist
Tuula Salo
Sabrina Daniela da Silva
Moulay A. Alaoui-Jamali
Edgard Graner
Jay W. Fox
Ricardo Della Coletta
Adriana Franco Paes Leme
author_sort Carolina Moretto Carnielli
title Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
title_short Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
title_full Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
title_fullStr Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
title_full_unstemmed Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
title_sort combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/1b7cd93db80e4a69b02dbb19996d562c
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