NOTCH4 Exhibits Anti-Inflammatory Activity in Activated Macrophages by Interfering With Interferon-γ and TLR4 Signaling
NOTCH4 is a member of the NOTCH family of receptors whose expression is intensively induced in macrophages after their activation by Toll-like receptors (TLR) and/or interferon-γ (IFN-γ). In this work, we show that this receptor acts as a negative regulator of macrophage activation by diminishing th...
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Autores principales: | Susana López-López, María José Romero de Ávila, Natalia Carolina Hernández de León, Francisco Ruiz-Marcos, Victoriano Baladrón, María Luisa Nueda, Jorge Laborda, José Javier García-Ramírez, Eva M. Monsalve, María José M. Díaz-Guerra |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/1b8d94105a284db482368c8e152f64b1 |
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