Manganese dioxide nanosheets: from preparation to biomedical applications

Muyu Wu,*,1,2 Pingfu Hou*,3, Lina Dong,1 Lulu Cai,1 Zhudian Chen,1 Mingming Zhao,1 Jingjing Li1–2,41School of Medical Imaging, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China; 2Department of Radiology, Affiliated Hospital of Xuzhou Medical University...

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Autores principales: Wu M, Hou P, Dong L, Cai L, Chen Z, Zhao M, Li J
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Publicado: Dove Medical Press 2019
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spelling oai:doaj.org-article:1b951c9b6d4f4f75987a86f00a28f5292021-12-02T03:07:56ZManganese dioxide nanosheets: from preparation to biomedical applications1178-2013https://doaj.org/article/1b951c9b6d4f4f75987a86f00a28f5292019-07-01T00:00:00Zhttps://www.dovepress.com/manganese-dioxide-nanosheets-from-preparation-to-biomedical-applicatio-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Muyu Wu,*,1,2 Pingfu Hou*,3, Lina Dong,1 Lulu Cai,1 Zhudian Chen,1 Mingming Zhao,1 Jingjing Li1–2,41School of Medical Imaging, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China; 2Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu, People’s Republic of China; 3Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China; 4Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China*These authors contributed equally to this workAbstract: Advancements in nanotechnology and molecular biology have promoted the development of a diverse range of models to intervene in various disorders (from diagnosis to treatment and even theranostics). Manganese dioxide nanosheets (MnO2 NSs), a typical two-dimensional (2D) transition metal oxide of nanomaterial that possesses unique structure and distinct properties have been employed in multiple disciplines in recent decades, especially in the field of biomedicine, including biocatalysis, fluorescence sensing, magnetic resonance imaging and cargo-loading functionality. A brief overview of the different synthetic methodologies for MnO2 NSs and their state-of-the-art biomedical applications is presented below, as well as the challenges and future perspectives of MnO2 NSs.Keywords: MnO2 nanosheets, synthetic methods, biocatalysis, fluorescence sensing, controlled drug delivery, stimuli-activated imagingWu MHou PDong LCai LChen ZZhao MLi JDove Medical PressarticleMnO2 nanosheetsSynthetic methodsBiocatalysisFluorescence sensingControlled drug deliveryStimuli-activated imagingMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 14, Pp 4781-4800 (2019)
institution DOAJ
collection DOAJ
language EN
topic MnO2 nanosheets
Synthetic methods
Biocatalysis
Fluorescence sensing
Controlled drug delivery
Stimuli-activated imaging
Medicine (General)
R5-920
spellingShingle MnO2 nanosheets
Synthetic methods
Biocatalysis
Fluorescence sensing
Controlled drug delivery
Stimuli-activated imaging
Medicine (General)
R5-920
Wu M
Hou P
Dong L
Cai L
Chen Z
Zhao M
Li J
Manganese dioxide nanosheets: from preparation to biomedical applications
description Muyu Wu,*,1,2 Pingfu Hou*,3, Lina Dong,1 Lulu Cai,1 Zhudian Chen,1 Mingming Zhao,1 Jingjing Li1–2,41School of Medical Imaging, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China; 2Department of Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, Jiangsu, People’s Republic of China; 3Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China; 4Institute of Medical Imaging and Digital Medicine, Xuzhou Medical University, Xuzhou 221004, Jiangsu, People’s Republic of China*These authors contributed equally to this workAbstract: Advancements in nanotechnology and molecular biology have promoted the development of a diverse range of models to intervene in various disorders (from diagnosis to treatment and even theranostics). Manganese dioxide nanosheets (MnO2 NSs), a typical two-dimensional (2D) transition metal oxide of nanomaterial that possesses unique structure and distinct properties have been employed in multiple disciplines in recent decades, especially in the field of biomedicine, including biocatalysis, fluorescence sensing, magnetic resonance imaging and cargo-loading functionality. A brief overview of the different synthetic methodologies for MnO2 NSs and their state-of-the-art biomedical applications is presented below, as well as the challenges and future perspectives of MnO2 NSs.Keywords: MnO2 nanosheets, synthetic methods, biocatalysis, fluorescence sensing, controlled drug delivery, stimuli-activated imaging
format article
author Wu M
Hou P
Dong L
Cai L
Chen Z
Zhao M
Li J
author_facet Wu M
Hou P
Dong L
Cai L
Chen Z
Zhao M
Li J
author_sort Wu M
title Manganese dioxide nanosheets: from preparation to biomedical applications
title_short Manganese dioxide nanosheets: from preparation to biomedical applications
title_full Manganese dioxide nanosheets: from preparation to biomedical applications
title_fullStr Manganese dioxide nanosheets: from preparation to biomedical applications
title_full_unstemmed Manganese dioxide nanosheets: from preparation to biomedical applications
title_sort manganese dioxide nanosheets: from preparation to biomedical applications
publisher Dove Medical Press
publishDate 2019
url https://doaj.org/article/1b951c9b6d4f4f75987a86f00a28f529
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