DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.

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Detalles Bibliográficos
Autores principales:	Wanwen Zeng, Xi Chen, Zhana Duren, Yong Wang, Rui Jiang, Wing Hung Wong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1b95ca72225a421798a545948feed603
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spelling	oai:doaj.org-article:1b95ca72225a421798a545948feed6032021-12-02T17:32:23ZDC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data10.1038/s41467-019-12547-12041-1723https://doaj.org/article/1b95ca72225a421798a545948feed6032019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12547-1https://doaj.org/toc/2041-1723Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.Wanwen ZengXi ChenZhana DurenYong WangRui JiangWing Hung WongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
description	Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.
format	article
author	Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong
author_facet	Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong
author_sort	Wanwen Zeng
title	DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_short	DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_full	DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_fullStr	DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_full_unstemmed	DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_sort	dc3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1b95ca72225a421798a545948feed603
work_keys_str_mv	AT wanwenzeng dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT xichen dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT zhanaduren dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT yongwang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT ruijiang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT winghungwong dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
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DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

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