DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data

Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.

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Autores principales: Wanwen Zeng, Xi Chen, Zhana Duren, Yong Wang, Rui Jiang, Wing Hung Wong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1b95ca72225a421798a545948feed603
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spelling oai:doaj.org-article:1b95ca72225a421798a545948feed6032021-12-02T17:32:23ZDC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data10.1038/s41467-019-12547-12041-1723https://doaj.org/article/1b95ca72225a421798a545948feed6032019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12547-1https://doaj.org/toc/2041-1723Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.Wanwen ZengXi ChenZhana DurenYong WangRui JiangWing Hung WongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wanwen Zeng
Xi Chen
Zhana Duren
Yong Wang
Rui Jiang
Wing Hung Wong
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
description Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.
format article
author Wanwen Zeng
Xi Chen
Zhana Duren
Yong Wang
Rui Jiang
Wing Hung Wong
author_facet Wanwen Zeng
Xi Chen
Zhana Duren
Yong Wang
Rui Jiang
Wing Hung Wong
author_sort Wanwen Zeng
title DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_short DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_full DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_fullStr DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_full_unstemmed DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
title_sort dc3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/1b95ca72225a421798a545948feed603
work_keys_str_mv AT wanwenzeng dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
AT xichen dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
AT zhanaduren dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
AT yongwang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
AT ruijiang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
AT winghungwong dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata
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