DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data
Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.
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Nature Portfolio
2019
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oai:doaj.org-article:1b95ca72225a421798a545948feed6032021-12-02T17:32:23ZDC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data10.1038/s41467-019-12547-12041-1723https://doaj.org/article/1b95ca72225a421798a545948feed6032019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12547-1https://doaj.org/toc/2041-1723Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population.Wanwen ZengXi ChenZhana DurenYong WangRui JiangWing Hung WongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
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Science Q Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
description |
Single-cell omics analysis can reveal heterogeneity among individual cells at different levels. Here, the authors develop DC3, a computational method for joint analysis of various bulk and single-cell data from the same heterogeneous cell population. |
format |
article |
author |
Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong |
author_facet |
Wanwen Zeng Xi Chen Zhana Duren Yong Wang Rui Jiang Wing Hung Wong |
author_sort |
Wanwen Zeng |
title |
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
title_short |
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
title_full |
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
title_fullStr |
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
title_full_unstemmed |
DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
title_sort |
dc3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/1b95ca72225a421798a545948feed603 |
work_keys_str_mv |
AT wanwenzeng dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT xichen dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT zhanaduren dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT yongwang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT ruijiang dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata AT winghungwong dc3isamethodfordeconvolutionandcoupledclusteringfrombulkandsinglecellgenomicsdata |
_version_ |
1718380292642701312 |