Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromatid exchange in BLM helicase deficient cells.

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Detalles Bibliográficos
Autores principales:	Rohit Prakash, Thomas Sandoval, Florian Morati, Jennifer A. Zagelbaum, Pei-Xin Lim, Travis White, Brett Taylor, Raymond Wang, Emilie C. B. Desclos, Meghan R. Sullivan, Hayley L. Rein, Kara A. Bernstein, Przemek M. Krawczyk, Jean Gautier, Mauro Modesti, Fabio Vanoli, Maria Jasin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1b96dd6800dc4b43afc200198f18973b
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spelling	oai:doaj.org-article:1b96dd6800dc4b43afc200198f18973b2021-12-02T18:36:59ZDistinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex10.1038/s41467-021-24205-62041-1723https://doaj.org/article/1b96dd6800dc4b43afc200198f18973b2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24205-6https://doaj.org/toc/2041-1723Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromatid exchange in BLM helicase deficient cells.Rohit PrakashThomas SandovalFlorian MoratiJennifer A. ZagelbaumPei-Xin LimTravis WhiteBrett TaylorRaymond WangEmilie C. B. DesclosMeghan R. SullivanHayley L. ReinKara A. BernsteinPrzemek M. KrawczykJean GautierMauro ModestiFabio VanoliMaria JasinNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rohit Prakash Thomas Sandoval Florian Morati Jennifer A. Zagelbaum Pei-Xin Lim Travis White Brett Taylor Raymond Wang Emilie C. B. Desclos Meghan R. Sullivan Hayley L. Rein Kara A. Bernstein Przemek M. Krawczyk Jean Gautier Mauro Modesti Fabio Vanoli Maria Jasin Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
description	Human SWS1, SWSAP1, and SPIDR interact with RAD51, a critical protein for homology-directed repair. Here the authors reveal roles for the mouse SWS1–SWSAP1–SPIDR complex in inter-homolog recombination, including during meiosis, and sister chromatid exchange in BLM helicase deficient cells.
format	article
author	Rohit Prakash Thomas Sandoval Florian Morati Jennifer A. Zagelbaum Pei-Xin Lim Travis White Brett Taylor Raymond Wang Emilie C. B. Desclos Meghan R. Sullivan Hayley L. Rein Kara A. Bernstein Przemek M. Krawczyk Jean Gautier Mauro Modesti Fabio Vanoli Maria Jasin
author_facet	Rohit Prakash Thomas Sandoval Florian Morati Jennifer A. Zagelbaum Pei-Xin Lim Travis White Brett Taylor Raymond Wang Emilie C. B. Desclos Meghan R. Sullivan Hayley L. Rein Kara A. Bernstein Przemek M. Krawczyk Jean Gautier Mauro Modesti Fabio Vanoli Maria Jasin
author_sort	Rohit Prakash
title	Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
title_short	Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
title_full	Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
title_fullStr	Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
title_full_unstemmed	Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex
title_sort	distinct pathways of homologous recombination controlled by the sws1–swsap1–spidr complex
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1b96dd6800dc4b43afc200198f18973b
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Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

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