Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis

Nitrogen-centered radicals are valuable intermediates for the controllable and selective functionalization of remote inert C(sp3)–H bonds. Here, the authors report an amidyl radical-triggered, metal-free and site-selective C(sp3)–H heteroarylation of amides under photoredox conditions.

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Autores principales:	Hui Chen, Wenjing Fan, Xiang-Ai Yuan, Shouyun Yu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1b9945378c72441bb7b2843a65f6e788
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spelling	oai:doaj.org-article:1b9945378c72441bb7b2843a65f6e7882021-12-02T16:57:11ZSite-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis10.1038/s41467-019-12722-42041-1723https://doaj.org/article/1b9945378c72441bb7b2843a65f6e7882019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12722-4https://doaj.org/toc/2041-1723Nitrogen-centered radicals are valuable intermediates for the controllable and selective functionalization of remote inert C(sp3)–H bonds. Here, the authors report an amidyl radical-triggered, metal-free and site-selective C(sp3)–H heteroarylation of amides under photoredox conditions.Hui ChenWenjing FanXiang-Ai YuanShouyun YuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hui Chen Wenjing Fan Xiang-Ai Yuan Shouyun Yu Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
description	Nitrogen-centered radicals are valuable intermediates for the controllable and selective functionalization of remote inert C(sp3)–H bonds. Here, the authors report an amidyl radical-triggered, metal-free and site-selective C(sp3)–H heteroarylation of amides under photoredox conditions.
format	article
author	Hui Chen Wenjing Fan Xiang-Ai Yuan Shouyun Yu
author_facet	Hui Chen Wenjing Fan Xiang-Ai Yuan Shouyun Yu
author_sort	Hui Chen
title	Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
title_short	Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
title_full	Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
title_fullStr	Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
title_full_unstemmed	Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis
title_sort	site-selective remote c(sp3)–h heteroarylation of amides via organic photoredox catalysis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/1b9945378c72441bb7b2843a65f6e788
work_keys_str_mv	AT huichen siteselectiveremotecsp3hheteroarylationofamidesviaorganicphotoredoxcatalysis AT wenjingfan siteselectiveremotecsp3hheteroarylationofamidesviaorganicphotoredoxcatalysis AT xiangaiyuan siteselectiveremotecsp3hheteroarylationofamidesviaorganicphotoredoxcatalysis AT shouyunyu siteselectiveremotecsp3hheteroarylationofamidesviaorganicphotoredoxcatalysis
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Site-selective remote C(sp3)–H heteroarylation of amides via organic photoredox catalysis

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