4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation

4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation

This manuscript deals with the synthesis and computational and experimental evaluation of the antimicrobial activity of twenty-nine 4-(indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole acylamines. An evaluation of antibacterial activity against Gram (+) and Gram (−) bacteria revealed that the M...

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Bibliographic Details
Main Authors: Sergei Simakov, Victor Kartsev, Anthi Petrou, Ioannis Nicolaou, Athina Geronikaki, Marija Ivanov, Marina Kostic, Jasmina Glamočlija, Marina Soković, Despoina Talea, Ioannis S. Vizirianakis
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
4-(indol-3-yl)thiazole-2-amines
4-ιndol-3-yl)thiazole acylamines
antimicrobial
antifungal
docking
Medicine
R
Pharmacy and materia medica
RS1-441
Online Access:https://doaj.org/article/1bae1751f15a47b794a3fea7fe68d3d5
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