Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards hi...
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| Formato: | article |
| Lenguaje: | EN |
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Dove Medical Press
2012
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| Acceso en línea: | https://doaj.org/article/1bb5efb74e044186b11454282b69ad43 |
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| Sumario: | Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards higher concentrations with age."2 The latter conclusion was based on a study that analyzed the age-specific distribution of serum TSH in 14,376 disease-free subjects with negative thyroid antibody tests. In that study, the percentage of TSH measurements in the 2.5–4.5 mIU/L range progressively increased with age from approximately 6.5% in the 20–29-year age group to 23.9% in the 80 years and older age group. Likewise, the percentage of TSH measurements in the .4.5 mIU/L category progressively increased from 2.0% in the 20–29-year age group to 12% in the 80 years and older age group.View original paper by Bensenor and colleagues.Corrigendum for this letter has been published |
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