Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age

Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards hi...

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Autor principal: Jolobe OM
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2012
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TSH
age
Acceso en línea:https://doaj.org/article/1bb5efb74e044186b11454282b69ad43
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spelling oai:doaj.org-article:1bb5efb74e044186b11454282b69ad432021-12-02T04:11:26ZUpper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age1178-1998https://doaj.org/article/1bb5efb74e044186b11454282b69ad432012-08-01T00:00:00Zhttps://www.dovepress.com/upper-limit-of-the-normal-range-for-thyrotropin-stimulating-hormone-is-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards higher concentrations with age."2 The latter conclusion was based on a study that analyzed the age-specific distribution of serum TSH in 14,376 disease-free subjects with negative thyroid antibody tests. In that study, the percentage of TSH measurements in the 2.5–4.5 mIU/L range progressively increased with age from approximately 6.5% in the 20–29-year age group to 23.9% in the 80 years and older age group. Likewise, the percentage of TSH measurements in the .4.5 mIU/L category progressively increased from 2.0% in the 20–29-year age group to 12% in the 80 years and older age group.View original paper by Bensenor and colleagues.Corrigendum for this letter has been published Jolobe OMDove Medical PressarticleUpper;limitTSHincreasingageGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 7, Pp 299-301 (2012)
institution DOAJ
collection DOAJ
language EN
topic Upper;limit
TSH
increasing
age
Geriatrics
RC952-954.6
spellingShingle Upper;limit
TSH
increasing
age
Geriatrics
RC952-954.6
Jolobe OM
Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
description Oscar MP JolobeManchester Medical Society, Manchester, United KingdomThe assertion that aging is associated with a decreasing concentration of thyrotropin-stimulating hormone (TSH) in healthy elderly humans1 appears to be at odds with the observation that "TSH distribution shifts towards higher concentrations with age."2 The latter conclusion was based on a study that analyzed the age-specific distribution of serum TSH in 14,376 disease-free subjects with negative thyroid antibody tests. In that study, the percentage of TSH measurements in the 2.5–4.5 mIU/L range progressively increased with age from approximately 6.5% in the 20–29-year age group to 23.9% in the 80 years and older age group. Likewise, the percentage of TSH measurements in the .4.5 mIU/L category progressively increased from 2.0% in the 20–29-year age group to 12% in the 80 years and older age group.View original paper by Bensenor and colleagues.Corrigendum for this letter has been published 
format article
author Jolobe OM
author_facet Jolobe OM
author_sort Jolobe OM
title Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
title_short Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
title_full Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
title_fullStr Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
title_full_unstemmed Upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
title_sort upper limit of the normal range for thyrotropin-stimulating hormone is higher with increasing age
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/1bb5efb74e044186b11454282b69ad43
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