Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs

Effective screening of drugs to treat amyloid oligomeric aggregates associated with Alzheimer’s is needed for drug development. Here the authors report on the creation of an amyloid corona around a plasmonic nanoparticle to monitor amyloid degradation when exposed to potential drugs and demonstrate...

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Autores principales:	Dongtak Lee, Dongsung Park, Insu Kim, Sang Won Lee, Wonseok Lee, Kyo Seon Hwang, Jeong Hoon Lee, Gyudo Lee, Dae Sung Yoon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1bb9cb18a1fd4795883af0c9b3b04454
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spelling	oai:doaj.org-article:1bb9cb18a1fd4795883af0c9b3b044542021-12-02T14:16:13ZPlasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs10.1038/s41467-020-20611-42041-1723https://doaj.org/article/1bb9cb18a1fd4795883af0c9b3b044542021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20611-4https://doaj.org/toc/2041-1723Effective screening of drugs to treat amyloid oligomeric aggregates associated with Alzheimer’s is needed for drug development. Here the authors report on the creation of an amyloid corona around a plasmonic nanoparticle to monitor amyloid degradation when exposed to potential drugs and demonstrate application.Dongtak LeeDongsung ParkInsu KimSang Won LeeWonseok LeeKyo Seon HwangJeong Hoon LeeGyudo LeeDae Sung YoonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dongtak Lee Dongsung Park Insu Kim Sang Won Lee Wonseok Lee Kyo Seon Hwang Jeong Hoon Lee Gyudo Lee Dae Sung Yoon Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
description	Effective screening of drugs to treat amyloid oligomeric aggregates associated with Alzheimer’s is needed for drug development. Here the authors report on the creation of an amyloid corona around a plasmonic nanoparticle to monitor amyloid degradation when exposed to potential drugs and demonstrate application.
format	article
author	Dongtak Lee Dongsung Park Insu Kim Sang Won Lee Wonseok Lee Kyo Seon Hwang Jeong Hoon Lee Gyudo Lee Dae Sung Yoon
author_facet	Dongtak Lee Dongsung Park Insu Kim Sang Won Lee Wonseok Lee Kyo Seon Hwang Jeong Hoon Lee Gyudo Lee Dae Sung Yoon
author_sort	Dongtak Lee
title	Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
title_short	Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
title_full	Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
title_fullStr	Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
title_full_unstemmed	Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs
title_sort	plasmonic nanoparticle amyloid corona for screening aβ oligomeric aggregate-degrading drugs
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1bb9cb18a1fd4795883af0c9b3b04454
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Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs

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