Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report

Abstract Background Kawasaki disease (KD) is an acute febrile vasculitis that often occurs in children under 5 years. Ptosis and muscle weakness associated with KD are rarely documented. Case presentation We present a case of KD with eyelid ptosis and muscle weakness in a 3-year-old boy. At admissio...

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Autores principales:	Yao Lin, Lijun Wang, Aijie Li, Hongwei Zhang, Lin Shi
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Kawasaki disease Ptosis Muscle weakness Myositis Case report Pediatrics RJ1-570
Acceso en línea:	https://doaj.org/article/1bc751d2ea654605a0aa4e70133c7434
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spelling	oai:doaj.org-article:1bc751d2ea654605a0aa4e70133c74342021-11-28T12:30:11ZEyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report10.1186/s12887-021-02979-41471-2431https://doaj.org/article/1bc751d2ea654605a0aa4e70133c74342021-11-01T00:00:00Zhttps://doi.org/10.1186/s12887-021-02979-4https://doaj.org/toc/1471-2431Abstract Background Kawasaki disease (KD) is an acute febrile vasculitis that often occurs in children under 5 years. Ptosis and muscle weakness associated with KD are rarely documented. Case presentation We present a case of KD with eyelid ptosis and muscle weakness in a 3-year-old boy. At admission, grade IV and grade III muscle strength were recorded for upper and lower limbs, respectively. Diminished patellar tendon reflex was noted. Laboratory evaluation showed hypokalemia with the serum potassium concentration of 2.62 mmol/L. Intravenous immunoglobulin (IVIG) and aspirin were initiated immediately accompanied with methylprednisolone for adjunctive therapy. Potassium supplement was administered at the same time, which resulted in the correction of hypokalemia on the 2nd day of admission but no improvement in ptosis and muscle weakness. Neostigmine testing, lumber puncture, electromyography, and cerebral and full spine MRI were performed, which, however, did not find evidence for neural and muscle diseases. On the 5th day, the fever was resolved. On the 6th day, eyelid ptosis disappeared. And on the 14th day, the muscle strength and muscle tension returned to normal, patellar tendon reflex could be drawn out normally, and the boy regained full ambulatory ability. Conclusions KD might affect the neural and muscular systems, and KD complicated with eyelid ptosis and muscle weakness is responsive to the standard anti-inflammatory treatment plus adjunctive corticosteroid therapy.Yao LinLijun WangAijie LiHongwei ZhangLin ShiBMCarticleKawasaki diseasePtosisMuscle weaknessMyositisCase reportPediatricsRJ1-570ENBMC Pediatrics, Vol 21, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Kawasaki disease Ptosis Muscle weakness Myositis Case report Pediatrics RJ1-570
spellingShingle	Kawasaki disease Ptosis Muscle weakness Myositis Case report Pediatrics RJ1-570 Yao Lin Lijun Wang Aijie Li Hongwei Zhang Lin Shi Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
description	Abstract Background Kawasaki disease (KD) is an acute febrile vasculitis that often occurs in children under 5 years. Ptosis and muscle weakness associated with KD are rarely documented. Case presentation We present a case of KD with eyelid ptosis and muscle weakness in a 3-year-old boy. At admission, grade IV and grade III muscle strength were recorded for upper and lower limbs, respectively. Diminished patellar tendon reflex was noted. Laboratory evaluation showed hypokalemia with the serum potassium concentration of 2.62 mmol/L. Intravenous immunoglobulin (IVIG) and aspirin were initiated immediately accompanied with methylprednisolone for adjunctive therapy. Potassium supplement was administered at the same time, which resulted in the correction of hypokalemia on the 2nd day of admission but no improvement in ptosis and muscle weakness. Neostigmine testing, lumber puncture, electromyography, and cerebral and full spine MRI were performed, which, however, did not find evidence for neural and muscle diseases. On the 5th day, the fever was resolved. On the 6th day, eyelid ptosis disappeared. And on the 14th day, the muscle strength and muscle tension returned to normal, patellar tendon reflex could be drawn out normally, and the boy regained full ambulatory ability. Conclusions KD might affect the neural and muscular systems, and KD complicated with eyelid ptosis and muscle weakness is responsive to the standard anti-inflammatory treatment plus adjunctive corticosteroid therapy.
format	article
author	Yao Lin Lijun Wang Aijie Li Hongwei Zhang Lin Shi
author_facet	Yao Lin Lijun Wang Aijie Li Hongwei Zhang Lin Shi
author_sort	Yao Lin
title	Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
title_short	Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
title_full	Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
title_fullStr	Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
title_full_unstemmed	Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report
title_sort	eyelid ptosis and muscle weakness in a child with kawasaki disease: a case report
publisher	BMC
publishDate	2021
url	https://doaj.org/article/1bc751d2ea654605a0aa4e70133c7434
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Eyelid ptosis and muscle weakness in a child with Kawasaki disease: a case report

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