Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration

Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration

Brüggeret al. identify part of the molecular machinery that controls Schwann cell development after peripheral nerve injury. Inhibiting HDAC1/2 early after injury enhances nerve regeneration and promotes functional recovery.

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Autores principales: Valérie Brügger, Mert Duman, Maëlle Bochud, Emmanuelle Münger, Manfred Heller, Sophie Ruff, Claire Jacob
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/1bcc71199b3443bd959d41fc82920f4f
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