Human adaptation and population differentiation in the light of ancient genomes

Detecting the targets of positive selection in the human genome is challenging. Here, the authors combine modern and ancient genomes to show that alleles strongly differentiated between Africans and Europeans mediated local adaptation in European populations, and were mostly contributed by ancient h...

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Autores principales:	Felix M. Key, Qiaomei Fu, Frédéric Romagné, Michael Lachmann, Aida M. Andrés
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1be2eb237c5f4c1590dc4d4036e3f8cc
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spelling	oai:doaj.org-article:1be2eb237c5f4c1590dc4d4036e3f8cc2021-12-02T14:40:14ZHuman adaptation and population differentiation in the light of ancient genomes10.1038/ncomms107752041-1723https://doaj.org/article/1be2eb237c5f4c1590dc4d4036e3f8cc2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10775https://doaj.org/toc/2041-1723Detecting the targets of positive selection in the human genome is challenging. Here, the authors combine modern and ancient genomes to show that alleles strongly differentiated between Africans and Europeans mediated local adaptation in European populations, and were mostly contributed by ancient hunter-gatherers.Felix M. KeyQiaomei FuFrédéric RomagnéMichael LachmannAida M. AndrésNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Felix M. Key Qiaomei Fu Frédéric Romagné Michael Lachmann Aida M. Andrés Human adaptation and population differentiation in the light of ancient genomes
description	Detecting the targets of positive selection in the human genome is challenging. Here, the authors combine modern and ancient genomes to show that alleles strongly differentiated between Africans and Europeans mediated local adaptation in European populations, and were mostly contributed by ancient hunter-gatherers.
format	article
author	Felix M. Key Qiaomei Fu Frédéric Romagné Michael Lachmann Aida M. Andrés
author_facet	Felix M. Key Qiaomei Fu Frédéric Romagné Michael Lachmann Aida M. Andrés
author_sort	Felix M. Key
title	Human adaptation and population differentiation in the light of ancient genomes
title_short	Human adaptation and population differentiation in the light of ancient genomes
title_full	Human adaptation and population differentiation in the light of ancient genomes
title_fullStr	Human adaptation and population differentiation in the light of ancient genomes
title_full_unstemmed	Human adaptation and population differentiation in the light of ancient genomes
title_sort	human adaptation and population differentiation in the light of ancient genomes
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/1be2eb237c5f4c1590dc4d4036e3f8cc
work_keys_str_mv	AT felixmkey humanadaptationandpopulationdifferentiationinthelightofancientgenomes AT qiaomeifu humanadaptationandpopulationdifferentiationinthelightofancientgenomes AT fredericromagne humanadaptationandpopulationdifferentiationinthelightofancientgenomes AT michaellachmann humanadaptationandpopulationdifferentiationinthelightofancientgenomes AT aidamandres humanadaptationandpopulationdifferentiationinthelightofancientgenomes
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Human adaptation and population differentiation in the light of ancient genomes

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