Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues

Abstract Although neurovascular compression of the cochlear nerve (NVC-C) presenting as typewriter tinnitus is a discrete disease category, verified diagnostic criteria are lacking. We sought to refine the diagnostic criteria for NVC-C by reference to a relatively large case series. The medical reco...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Woongsang Sunwoo, Yung Jin Jeon, Yun Jung Bae, Jeong Hun Jang, Ja-Won Koo, Jae-Jin Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1be534d0e6d3470092a7133d0b562a1c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1be534d0e6d3470092a7133d0b562a1c
record_format	dspace
spelling	oai:doaj.org-article:1be534d0e6d3470092a7133d0b562a1c2021-12-02T15:04:59ZTypewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues10.1038/s41598-017-10798-w2045-2322https://doaj.org/article/1be534d0e6d3470092a7133d0b562a1c2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-10798-whttps://doaj.org/toc/2045-2322Abstract Although neurovascular compression of the cochlear nerve (NVC-C) presenting as typewriter tinnitus is a discrete disease category, verified diagnostic criteria are lacking. We sought to refine the diagnostic criteria for NVC-C by reference to a relatively large case series. The medical records of 22 NVC-C patients were retrospectively reviewed. Psychoacoustic characteristics, the results of diagnostic work-up (including audiovestibular neurophysiological tests and radiological evaluations), and the initial treatment response to carbamazepine were investigated. All subjects described their tinnitus as a typical “typewriter” or “staccato” sound. Of the 22 subjects, 11 (50%) had histories of vertiginous spells, but none had ipsilesional hearing loss. Vestibular function tests in 11 subjects tested revealed only 2 (18.2%) isolated cervical vestibular evoked myogenic potential abnormalities. Radiological comparisons of the symptomatic and asymptomatic sides, regarding the type of the vascular loop and neurovascular contact, revealed no significant differences. However, all 22 subjects exhibited immediate and marked responses to short-term carbamazepine treatment. Meticulous history-taking in terms of the psychoacoustic characteristics and the response to initial carbamazepine, are more reliable diagnostic clues than are radiological or neurophysiological data in NVC-C subjects. Therefore, the typical psychoacoustic characteristics and the response to initial carbamazepine should be included in the diagnostic criteria.Woongsang SunwooYung Jin JeonYun Jung BaeJeong Hun JangJa-Won KooJae-Jin SongNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Woongsang Sunwoo Yung Jin Jeon Yun Jung Bae Jeong Hun Jang Ja-Won Koo Jae-Jin Song Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
description	Abstract Although neurovascular compression of the cochlear nerve (NVC-C) presenting as typewriter tinnitus is a discrete disease category, verified diagnostic criteria are lacking. We sought to refine the diagnostic criteria for NVC-C by reference to a relatively large case series. The medical records of 22 NVC-C patients were retrospectively reviewed. Psychoacoustic characteristics, the results of diagnostic work-up (including audiovestibular neurophysiological tests and radiological evaluations), and the initial treatment response to carbamazepine were investigated. All subjects described their tinnitus as a typical “typewriter” or “staccato” sound. Of the 22 subjects, 11 (50%) had histories of vertiginous spells, but none had ipsilesional hearing loss. Vestibular function tests in 11 subjects tested revealed only 2 (18.2%) isolated cervical vestibular evoked myogenic potential abnormalities. Radiological comparisons of the symptomatic and asymptomatic sides, regarding the type of the vascular loop and neurovascular contact, revealed no significant differences. However, all 22 subjects exhibited immediate and marked responses to short-term carbamazepine treatment. Meticulous history-taking in terms of the psychoacoustic characteristics and the response to initial carbamazepine, are more reliable diagnostic clues than are radiological or neurophysiological data in NVC-C subjects. Therefore, the typical psychoacoustic characteristics and the response to initial carbamazepine should be included in the diagnostic criteria.
format	article
author	Woongsang Sunwoo Yung Jin Jeon Yun Jung Bae Jeong Hun Jang Ja-Won Koo Jae-Jin Song
author_facet	Woongsang Sunwoo Yung Jin Jeon Yun Jung Bae Jeong Hun Jang Ja-Won Koo Jae-Jin Song
author_sort	Woongsang Sunwoo
title	Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
title_short	Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
title_full	Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
title_fullStr	Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
title_full_unstemmed	Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
title_sort	typewriter tinnitus revisited: the typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1be534d0e6d3470092a7133d0b562a1c
work_keys_str_mv	AT woongsangsunwoo typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues AT yungjinjeon typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues AT yunjungbae typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues AT jeonghunjang typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues AT jawonkoo typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues AT jaejinsong typewritertinnitusrevisitedthetypicalsymptomsandtheinitialresponsetocarbamazepinearethemostreliablediagnosticclues
_version_	1718388940747046912

Typewriter tinnitus revisited: The typical symptoms and the initial response to carbamazepine are the most reliable diagnostic clues

Ejemplares similares