Nature of the Interplay Between Periodontal Diseases and COVID-19

The coronavirus disease 2019 (COVID-19) is mostly a mild condition, however, in some patients, it could progress into a severe and even fatal disease. Recent studies have shown that COVID-19 infection and severity could be associated with the presence of periodontitis, one of the most prevalent chro...

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Autores principales:	Wenji Cai, Nadya Marouf, Khalid N. Said, Faleh Tamimi
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	COVID-19 periodontitis SARS-CoV-2 (2019-nCoV) cytokine storm ACE2 (angiotensin converting enzyme-2) co-infection Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/1be8533aa9034013972daf824dcc5346
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spelling	oai:doaj.org-article:1be8533aa9034013972daf824dcc53462021-12-03T05:19:11ZNature of the Interplay Between Periodontal Diseases and COVID-192673-491510.3389/fdmed.2021.735126https://doaj.org/article/1be8533aa9034013972daf824dcc53462021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fdmed.2021.735126/fullhttps://doaj.org/toc/2673-4915The coronavirus disease 2019 (COVID-19) is mostly a mild condition, however, in some patients, it could progress into a severe and even fatal disease. Recent studies have shown that COVID-19 infection and severity could be associated with the presence of periodontitis, one of the most prevalent chronic diseases. This association could be explained by the fact that periodontitis and COVID-19 share some common risk factors that included chronic diseases, such as diabetes and hypertension as well as conditions such as age, sex, and genetic variants. Another possible explanation could be the systemic inflammation and the aspiration of periodontopathogens seen in patients with periodontitis, which could have a synergism with the virus or compromise the reaction of the body against COVID-19. This narrative review explores the nature of these associations, the evidence behind them, and their implications.Wenji CaiNadya MaroufKhalid N. SaidFaleh TamimiFrontiers Media S.A.articleCOVID-19periodontitisSARS-CoV-2 (2019-nCoV)cytokine stormACE2 (angiotensin converting enzyme-2)co-infectionDentistryRK1-715ENFrontiers in Dental Medicine, Vol 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 periodontitis SARS-CoV-2 (2019-nCoV) cytokine storm ACE2 (angiotensin converting enzyme-2) co-infection Dentistry RK1-715
spellingShingle	COVID-19 periodontitis SARS-CoV-2 (2019-nCoV) cytokine storm ACE2 (angiotensin converting enzyme-2) co-infection Dentistry RK1-715 Wenji Cai Nadya Marouf Khalid N. Said Faleh Tamimi Nature of the Interplay Between Periodontal Diseases and COVID-19
description	The coronavirus disease 2019 (COVID-19) is mostly a mild condition, however, in some patients, it could progress into a severe and even fatal disease. Recent studies have shown that COVID-19 infection and severity could be associated with the presence of periodontitis, one of the most prevalent chronic diseases. This association could be explained by the fact that periodontitis and COVID-19 share some common risk factors that included chronic diseases, such as diabetes and hypertension as well as conditions such as age, sex, and genetic variants. Another possible explanation could be the systemic inflammation and the aspiration of periodontopathogens seen in patients with periodontitis, which could have a synergism with the virus or compromise the reaction of the body against COVID-19. This narrative review explores the nature of these associations, the evidence behind them, and their implications.
format	article
author	Wenji Cai Nadya Marouf Khalid N. Said Faleh Tamimi
author_facet	Wenji Cai Nadya Marouf Khalid N. Said Faleh Tamimi
author_sort	Wenji Cai
title	Nature of the Interplay Between Periodontal Diseases and COVID-19
title_short	Nature of the Interplay Between Periodontal Diseases and COVID-19
title_full	Nature of the Interplay Between Periodontal Diseases and COVID-19
title_fullStr	Nature of the Interplay Between Periodontal Diseases and COVID-19
title_full_unstemmed	Nature of the Interplay Between Periodontal Diseases and COVID-19
title_sort	nature of the interplay between periodontal diseases and covid-19
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/1be8533aa9034013972daf824dcc5346
work_keys_str_mv	AT wenjicai natureoftheinterplaybetweenperiodontaldiseasesandcovid19 AT nadyamarouf natureoftheinterplaybetweenperiodontaldiseasesandcovid19 AT khalidnsaid natureoftheinterplaybetweenperiodontaldiseasesandcovid19 AT falehtamimi natureoftheinterplaybetweenperiodontaldiseasesandcovid19
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Nature of the Interplay Between Periodontal Diseases and COVID-19

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