Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics in islets and br...

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Autores principales: Julia Ast, Anastasia Arvaniti, Nicholas H. F. Fine, Daniela Nasteska, Fiona B. Ashford, Zania Stamataki, Zsombor Koszegi, Andrea Bacon, Ben J. Jones, Maria A. Lucey, Shugo Sasaki, Daniel I. Brierley, Benoit Hastoy, Alejandra Tomas, Giuseppe D’Agostino, Frank Reimann, Francis C. Lynn, Christopher A. Reissaus, Amelia K. Linnemann, Elisa D’Este, Davide Calebiro, Stefan Trapp, Kai Johnsson, Tom Podewin, Johannes Broichhagen, David J. Hodson
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/1bec881e08194ff3b4ad84658e067529
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spelling oai:doaj.org-article:1bec881e08194ff3b4ad84658e0675292021-12-02T17:33:12ZSuper-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics10.1038/s41467-020-14309-w2041-1723https://doaj.org/article/1bec881e08194ff3b4ad84658e0675292020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14309-whttps://doaj.org/toc/2041-1723Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics in islets and brain.Julia AstAnastasia ArvanitiNicholas H. F. FineDaniela NasteskaFiona B. AshfordZania StamatakiZsombor KoszegiAndrea BaconBen J. JonesMaria A. LuceyShugo SasakiDaniel I. BrierleyBenoit HastoyAlejandra TomasGiuseppe D’AgostinoFrank ReimannFrancis C. LynnChristopher A. ReissausAmelia K. LinnemannElisa D’EsteDavide CalebiroStefan TrappKai JohnssonTom PodewinJohannes BroichhagenDavid J. HodsonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julia Ast
Anastasia Arvaniti
Nicholas H. F. Fine
Daniela Nasteska
Fiona B. Ashford
Zania Stamataki
Zsombor Koszegi
Andrea Bacon
Ben J. Jones
Maria A. Lucey
Shugo Sasaki
Daniel I. Brierley
Benoit Hastoy
Alejandra Tomas
Giuseppe D’Agostino
Frank Reimann
Francis C. Lynn
Christopher A. Reissaus
Amelia K. Linnemann
Elisa D’Este
Davide Calebiro
Stefan Trapp
Kai Johnsson
Tom Podewin
Johannes Broichhagen
David J. Hodson
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
description Glucagon-like peptide-1 receptor is an important regulator of appetite and glucose homeostasis. Here the authors describe super-resolution microscopy and in vivo imaging compatible fluorescent probes, which reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics in islets and brain.
format article
author Julia Ast
Anastasia Arvaniti
Nicholas H. F. Fine
Daniela Nasteska
Fiona B. Ashford
Zania Stamataki
Zsombor Koszegi
Andrea Bacon
Ben J. Jones
Maria A. Lucey
Shugo Sasaki
Daniel I. Brierley
Benoit Hastoy
Alejandra Tomas
Giuseppe D’Agostino
Frank Reimann
Francis C. Lynn
Christopher A. Reissaus
Amelia K. Linnemann
Elisa D’Este
Davide Calebiro
Stefan Trapp
Kai Johnsson
Tom Podewin
Johannes Broichhagen
David J. Hodson
author_facet Julia Ast
Anastasia Arvaniti
Nicholas H. F. Fine
Daniela Nasteska
Fiona B. Ashford
Zania Stamataki
Zsombor Koszegi
Andrea Bacon
Ben J. Jones
Maria A. Lucey
Shugo Sasaki
Daniel I. Brierley
Benoit Hastoy
Alejandra Tomas
Giuseppe D’Agostino
Frank Reimann
Francis C. Lynn
Christopher A. Reissaus
Amelia K. Linnemann
Elisa D’Este
Davide Calebiro
Stefan Trapp
Kai Johnsson
Tom Podewin
Johannes Broichhagen
David J. Hodson
author_sort Julia Ast
title Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
title_short Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
title_full Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
title_fullStr Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
title_full_unstemmed Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
title_sort super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/1bec881e08194ff3b4ad84658e067529
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