Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia

Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia

ABSTRACT Secondary bacterial lung infection by Streptococcus pneumoniae (S. pneumoniae) poses a serious health concern, especially in developing countries. We posit that the emergence of multiantibiotic-resistant strains will jeopardize current treatments in these regions. Deaths arising from second...

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Autores principales: Liang Li, Benjamin Jie Wei Foo, Ka Wai Kwok, Noriho Sakamoto, Hiroshi Mukae, Koichi Izumikawa, Stéphane Mandard, Jean-Pierre Quenot, Laurent Lagrost, Wooi Keong Teh, Gurjeet Singh Kohli, Pengcheng Zhu, Hyungwon Choi, Martin Lindsay Buist, Ju Ee Seet, Liang Yang, Fang He, Vincent Tak Kwong Chow, Nguan Soon Tan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
ANGPTL4
secondary bacterial pneumonia
antibiotic resistance
host-directed immunotherapeutics
vascular permeability
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/1bf0767f133a40f4a35769c99d508b56
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