Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction
In this paper, the authors report the directed-evolution of translation systems that allow the incorporation of unnatural amino acids with similar efficiency to natural amino acids and the construction of synthetic auxotroph in a generalizable way.
Guardado en:
Autores principales: | Hongxia Zhao, Wenlong Ding, Jia Zang, Yang Yang, Chao Liu, Linzhen Hu, Yulin Chen, Guanglong Liu, Yu Fang, Ying Yuan, Shixian Lin |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1bf4b6f580834b37bd653778889991d8 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Incorporation of Unnatural Amino Acid into Antibody Fragment for Creating a Stable Antibody Drug Conjugate
por: Andri Wardiana, et al.
Publicado: (2021) -
Plasmid Curing and Exchange Using a Novel Counter-Selectable Marker Based on Unnatural Amino Acid Incorporation at a Sense Codon
por: Yusuke Kato
Publicado: (2021) -
Visible-light-mediated catalyst-free synthesis of unnatural α-amino acids and peptide macrocycles
por: Mengran Wang, et al.
Publicado: (2021) -
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion
por: Wenlong Ding, et al.
Publicado: (2020) -
Biomolecular simulation based machine learning models accurately predict sites of tolerability to the unnatural amino acid acridonylalanine
por: Sam Giannakoulias, et al.
Publicado: (2021)