Importance of Nano Medicine and New Drug Therapies for Cancer

Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired loc...

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Autores principales:	Arash Abdolmaleki, Asadollah Asadi, Krishnamoorthy Gurushankar, Tahereh Karimi Shayan, Fatemeh Abedi Sarvestani
Formato:	article
Lenguaje:	EN
Publicado:	Tabriz University of Medical Sciences 2020
Materias:	cancer drug nanomedicine drug delivery system Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/1c094698370847219f8ed90d31cb334c
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spelling	oai:doaj.org-article:1c094698370847219f8ed90d31cb334c2021-12-05T09:40:17ZImportance of Nano Medicine and New Drug Therapies for Cancer2228-58812251-730810.34172/apb.2021.052https://doaj.org/article/1c094698370847219f8ed90d31cb334c2020-10-01T00:00:00Zhttps://apb.tbzmed.ac.ir/PDF/apb-11-450.pdfhttps://doaj.org/toc/2228-5881https://doaj.org/toc/2251-7308Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired location. Thus, the influence of drugs on vital tissues and undesirable side effects can be minimised. Additionally, DDS protects the drug from rapid degradation or clearance and enhances drug concentration in target tissues, and therefore, minimise the required dose of drug. This modern form of therapy is particularly important when there is a discrepancy between the dose and concentration of a drug. Cell-specific targeting can be achieved by attaching drugs to individually designed carriers. Recent developments in nanotechnology have shown that nanoparticles (particles with diameter < 100 nm in at least one dimension) have great potential as drug carriers. Because of their small size, these nanostructures exhibit unique physicochemical and biological properties that make them a favourable material for biomedical applications. Therefore, in this review, we aimed to describe the importance and types of nanomedicines and efficient ways in which new drug delivery systems for the treatment of cancer can be developed.Arash AbdolmalekiAsadollah AsadiKrishnamoorthy GurushankarTahereh Karimi ShayanFatemeh Abedi SarvestaniTabriz University of Medical Sciences articlecancerdrugnanomedicinedrug delivery systemTherapeutics. PharmacologyRM1-950ENAdvanced Pharmaceutical Bulletin, Vol 11, Iss 3, Pp 450-457 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cancer drug nanomedicine drug delivery system Therapeutics. Pharmacology RM1-950
spellingShingle	cancer drug nanomedicine drug delivery system Therapeutics. Pharmacology RM1-950 Arash Abdolmaleki Asadollah Asadi Krishnamoorthy Gurushankar Tahereh Karimi Shayan Fatemeh Abedi Sarvestani Importance of Nano Medicine and New Drug Therapies for Cancer
description	Cancer is one of the deadly diseases leading to approximately 7.6 million deaths worldwide, with the mortality rate of 13%, and the number of deaths is expected to increase to 13.1 million within the next 10 years. In controlled drug delivery systems (DDS), the drug is transported to the desired location. Thus, the influence of drugs on vital tissues and undesirable side effects can be minimised. Additionally, DDS protects the drug from rapid degradation or clearance and enhances drug concentration in target tissues, and therefore, minimise the required dose of drug. This modern form of therapy is particularly important when there is a discrepancy between the dose and concentration of a drug. Cell-specific targeting can be achieved by attaching drugs to individually designed carriers. Recent developments in nanotechnology have shown that nanoparticles (particles with diameter < 100 nm in at least one dimension) have great potential as drug carriers. Because of their small size, these nanostructures exhibit unique physicochemical and biological properties that make them a favourable material for biomedical applications. Therefore, in this review, we aimed to describe the importance and types of nanomedicines and efficient ways in which new drug delivery systems for the treatment of cancer can be developed.
format	article
author	Arash Abdolmaleki Asadollah Asadi Krishnamoorthy Gurushankar Tahereh Karimi Shayan Fatemeh Abedi Sarvestani
author_facet	Arash Abdolmaleki Asadollah Asadi Krishnamoorthy Gurushankar Tahereh Karimi Shayan Fatemeh Abedi Sarvestani
author_sort	Arash Abdolmaleki
title	Importance of Nano Medicine and New Drug Therapies for Cancer
title_short	Importance of Nano Medicine and New Drug Therapies for Cancer
title_full	Importance of Nano Medicine and New Drug Therapies for Cancer
title_fullStr	Importance of Nano Medicine and New Drug Therapies for Cancer
title_full_unstemmed	Importance of Nano Medicine and New Drug Therapies for Cancer
title_sort	importance of nano medicine and new drug therapies for cancer
publisher	Tabriz University of Medical Sciences
publishDate	2020
url	https://doaj.org/article/1c094698370847219f8ed90d31cb334c
work_keys_str_mv	AT arashabdolmaleki importanceofnanomedicineandnewdrugtherapiesforcancer AT asadollahasadi importanceofnanomedicineandnewdrugtherapiesforcancer AT krishnamoorthygurushankar importanceofnanomedicineandnewdrugtherapiesforcancer AT taherehkarimishayan importanceofnanomedicineandnewdrugtherapiesforcancer AT fatemehabedisarvestani importanceofnanomedicineandnewdrugtherapiesforcancer
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Importance of Nano Medicine and New Drug Therapies for Cancer

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