Ssu72 attenuates autoimmune arthritis via targeting of STAT3 signaling and Th17 activation
Abstract Signal transducer and activator of transcription 3 (STAT3) orchestrates the differentiation of several cell types, including interleukin-17 (IL-17)-releasing Th17 cells. Dysregulation of Th17 cells results in chronic inflammatory responses. Ssu72 is a C-terminal domain phosphatase required...
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Autores principales: | Seung Hoon Lee, Eun-Kyung Kim, Jeong-Eun Kwon, Jin-Kwan Lee, DoHyeong Lee, Se-Young Kim, Hyeon-Beom Seo, Hyun Sik Na, KyoungAh Jung, Seung-Ki Kwok, Chang-Woo Lee, Sung-Hwan Park, Mi-La Cho |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/1c1c977a45ce4269ab9119dafc2fbdfa |
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