EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS

Abstract. This study has shown that intravenous normal human immunoglobulin (IVIG), when included into combined therapy of acute epiglottitis, exerts positive effect upon clinical course of the disease and contributes to normalisation of immune status. Due to IVIG therapy, an increase in IgA and sIg...

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Autores principales:	A. V. Savchenko, N. N. Popov
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	intravenous normal human immunoglobulin acute epiglottitis Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/1c2002a0ad454bac83471004ef155bf8
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spelling	oai:doaj.org-article:1c2002a0ad454bac83471004ef155bf82021-11-18T08:03:37ZEFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS1563-06252313-741X10.15789/1563-0625-2008-1-71-76https://doaj.org/article/1c2002a0ad454bac83471004ef155bf82014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/83https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. This study has shown that intravenous normal human immunoglobulin (IVIG), when included into combined therapy of acute epiglottitis, exerts positive effect upon clinical course of the disease and contributes to normalisation of immune status. Due to IVIG therapy, an increase in IgA and sIgA concentrations is observed in laryngopharynx secretions. Amounts and affinity of serum antibodies to common bacterial antigenic determinant are increased in blood, as well as opsonizing properties of blood serum. Moreover, a higher phagocytic and bactericidal activity of neutrophils is observed with such treatment. Inflammatory as well as degenerative and destructive processes in epiglottis seem to be preventable under the influence of IVIG therapy.A. V. SavchenkoN. N. PopovSPb RAACIarticleintravenous normal human immunoglobulinacute epiglottitisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 1, Pp 71-76 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	intravenous normal human immunoglobulin acute epiglottitis Immunologic diseases. Allergy RC581-607
spellingShingle	intravenous normal human immunoglobulin acute epiglottitis Immunologic diseases. Allergy RC581-607 A. V. Savchenko N. N. Popov EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
description	Abstract. This study has shown that intravenous normal human immunoglobulin (IVIG), when included into combined therapy of acute epiglottitis, exerts positive effect upon clinical course of the disease and contributes to normalisation of immune status. Due to IVIG therapy, an increase in IgA and sIgA concentrations is observed in laryngopharynx secretions. Amounts and affinity of serum antibodies to common bacterial antigenic determinant are increased in blood, as well as opsonizing properties of blood serum. Moreover, a higher phagocytic and bactericidal activity of neutrophils is observed with such treatment. Inflammatory as well as degenerative and destructive processes in epiglottis seem to be preventable under the influence of IVIG therapy.
format	article
author	A. V. Savchenko N. N. Popov
author_facet	A. V. Savchenko N. N. Popov
author_sort	A. V. Savchenko
title	EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
title_short	EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
title_full	EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
title_fullStr	EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
title_full_unstemmed	EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS
title_sort	effects of ivig treatment upon local and general immunity state in the patients with acute epiglottitis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/1c2002a0ad454bac83471004ef155bf8
work_keys_str_mv	AT avsavchenko effectsofivigtreatmentuponlocalandgeneralimmunitystateinthepatientswithacuteepiglottitis AT nnpopov effectsofivigtreatmentuponlocalandgeneralimmunitystateinthepatientswithacuteepiglottitis
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EFFECTS OF IVIG TREATMENT UPON LOCAL AND GENERAL IMMUNITY STATE IN THE PATIENTS WITH ACUTE EPIGLOTTITIS

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