Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity

Influenza A virus (IAV) and SARS-CoV-2 coinfection is a possible scenario during influenza season. Here, the authors show in a mouse model that IAV infection increases the risk of severe disease upon SARS-CoV-2 infection two days later. IAV vaccination, especially antibody-dependent, protects from s...

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Autores principales:	Hagit Achdout, Einat. B. Vitner, Boaz Politi, Sharon Melamed, Yfat Yahalom-Ronen, Hadas Tamir, Noam Erez, Roy Avraham, Shay Weiss, Lilach Cherry, Erez Bar-Haim, Efi Makdasi, David Gur, Moshe Aftalion, Theodor Chitlaru, Yaron Vagima, Nir Paran, Tomer Israely
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1c21769ac0654cd898e2ff49db5bd690
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spelling	oai:doaj.org-article:1c21769ac0654cd898e2ff49db5bd6902021-12-02T19:16:32ZIncreased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity10.1038/s41467-021-26113-12041-1723https://doaj.org/article/1c21769ac0654cd898e2ff49db5bd6902021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26113-1https://doaj.org/toc/2041-1723Influenza A virus (IAV) and SARS-CoV-2 coinfection is a possible scenario during influenza season. Here, the authors show in a mouse model that IAV infection increases the risk of severe disease upon SARS-CoV-2 infection two days later. IAV vaccination, especially antibody-dependent, protects from severe disease during coinfection.Hagit AchdoutEinat. B. VitnerBoaz PolitiSharon MelamedYfat Yahalom-RonenHadas TamirNoam ErezRoy AvrahamShay WeissLilach CherryErez Bar-HaimEfi MakdasiDavid GurMoshe AftalionTheodor ChitlaruYaron VagimaNir ParanTomer IsraelyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hagit Achdout Einat. B. Vitner Boaz Politi Sharon Melamed Yfat Yahalom-Ronen Hadas Tamir Noam Erez Roy Avraham Shay Weiss Lilach Cherry Erez Bar-Haim Efi Makdasi David Gur Moshe Aftalion Theodor Chitlaru Yaron Vagima Nir Paran Tomer Israely Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
description	Influenza A virus (IAV) and SARS-CoV-2 coinfection is a possible scenario during influenza season. Here, the authors show in a mouse model that IAV infection increases the risk of severe disease upon SARS-CoV-2 infection two days later. IAV vaccination, especially antibody-dependent, protects from severe disease during coinfection.
format	article
author	Hagit Achdout Einat. B. Vitner Boaz Politi Sharon Melamed Yfat Yahalom-Ronen Hadas Tamir Noam Erez Roy Avraham Shay Weiss Lilach Cherry Erez Bar-Haim Efi Makdasi David Gur Moshe Aftalion Theodor Chitlaru Yaron Vagima Nir Paran Tomer Israely
author_facet	Hagit Achdout Einat. B. Vitner Boaz Politi Sharon Melamed Yfat Yahalom-Ronen Hadas Tamir Noam Erez Roy Avraham Shay Weiss Lilach Cherry Erez Bar-Haim Efi Makdasi David Gur Moshe Aftalion Theodor Chitlaru Yaron Vagima Nir Paran Tomer Israely
author_sort	Hagit Achdout
title	Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
title_short	Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
title_full	Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
title_fullStr	Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
title_full_unstemmed	Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
title_sort	increased lethality in influenza and sars-cov-2 coinfection is prevented by influenza immunity but not sars-cov-2 immunity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1c21769ac0654cd898e2ff49db5bd690
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Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity

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