Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

The plasma membrane is enriched in phosphatidylserine (PtdSer) mostly localized at the inner leaflet, which is predicted to induce membrane curvature. Here the authors show that membrane curvature induced by the proximity of anionic phospholipids can induce endocytosis and that cholesterol limits sp...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Takashi Hirama, Stella M. Lu, Jason G. Kay, Masashi Maekawa, Michael M. Kozlov, Sergio Grinstein, Gregory D. Fairn
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1c22c972acee4860ae917618ded44d94
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:1c22c972acee4860ae917618ded44d94
record_format	dspace
spelling	oai:doaj.org-article:1c22c972acee4860ae917618ded44d942021-12-02T14:40:37ZMembrane curvature induced by proximity of anionic phospholipids can initiate endocytosis10.1038/s41467-017-01554-92041-1723https://doaj.org/article/1c22c972acee4860ae917618ded44d942017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01554-9https://doaj.org/toc/2041-1723The plasma membrane is enriched in phosphatidylserine (PtdSer) mostly localized at the inner leaflet, which is predicted to induce membrane curvature. Here the authors show that membrane curvature induced by the proximity of anionic phospholipids can induce endocytosis and that cholesterol limits spontaneous curvature.Takashi HiramaStella M. LuJason G. KayMasashi MaekawaMichael M. KozlovSergio GrinsteinGregory D. FairnNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Takashi Hirama Stella M. Lu Jason G. Kay Masashi Maekawa Michael M. Kozlov Sergio Grinstein Gregory D. Fairn Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
description	The plasma membrane is enriched in phosphatidylserine (PtdSer) mostly localized at the inner leaflet, which is predicted to induce membrane curvature. Here the authors show that membrane curvature induced by the proximity of anionic phospholipids can induce endocytosis and that cholesterol limits spontaneous curvature.
format	article
author	Takashi Hirama Stella M. Lu Jason G. Kay Masashi Maekawa Michael M. Kozlov Sergio Grinstein Gregory D. Fairn
author_facet	Takashi Hirama Stella M. Lu Jason G. Kay Masashi Maekawa Michael M. Kozlov Sergio Grinstein Gregory D. Fairn
author_sort	Takashi Hirama
title	Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
title_short	Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
title_full	Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
title_fullStr	Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
title_full_unstemmed	Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
title_sort	membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1c22c972acee4860ae917618ded44d94
work_keys_str_mv	AT takashihirama membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT stellamlu membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT jasongkay membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT masashimaekawa membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT michaelmkozlov membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT sergiogrinstein membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis AT gregorydfairn membranecurvatureinducedbyproximityofanionicphospholipidscaninitiateendocytosis
_version_	1718390219937415168

Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

Ejemplares similares