Plasma cell survival in the absence of B cell memory

The long-term maintenance of antibody-secreting plasma cells and the requirement for memory B cells are unclear. Here, the authors show that plasma cells and the antibodies secreted are long-lived and maintained over a decade in the absence of memory B cells in non-human primates.

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Autores principales:	Erika Hammarlund, Archana Thomas, Ian J. Amanna, Lindsay A. Holden, Ov D. Slayden, Byung Park, Lina Gao, Mark K. Slifka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1c247d33ca304c67924a5f0adaff21c2
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spelling	oai:doaj.org-article:1c247d33ca304c67924a5f0adaff21c22021-12-02T14:42:45ZPlasma cell survival in the absence of B cell memory10.1038/s41467-017-01901-w2041-1723https://doaj.org/article/1c247d33ca304c67924a5f0adaff21c22017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01901-whttps://doaj.org/toc/2041-1723The long-term maintenance of antibody-secreting plasma cells and the requirement for memory B cells are unclear. Here, the authors show that plasma cells and the antibodies secreted are long-lived and maintained over a decade in the absence of memory B cells in non-human primates.Erika HammarlundArchana ThomasIan J. AmannaLindsay A. HoldenOv D. SlaydenByung ParkLina GaoMark K. SlifkaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erika Hammarlund Archana Thomas Ian J. Amanna Lindsay A. Holden Ov D. Slayden Byung Park Lina Gao Mark K. Slifka Plasma cell survival in the absence of B cell memory
description	The long-term maintenance of antibody-secreting plasma cells and the requirement for memory B cells are unclear. Here, the authors show that plasma cells and the antibodies secreted are long-lived and maintained over a decade in the absence of memory B cells in non-human primates.
format	article
author	Erika Hammarlund Archana Thomas Ian J. Amanna Lindsay A. Holden Ov D. Slayden Byung Park Lina Gao Mark K. Slifka
author_facet	Erika Hammarlund Archana Thomas Ian J. Amanna Lindsay A. Holden Ov D. Slayden Byung Park Lina Gao Mark K. Slifka
author_sort	Erika Hammarlund
title	Plasma cell survival in the absence of B cell memory
title_short	Plasma cell survival in the absence of B cell memory
title_full	Plasma cell survival in the absence of B cell memory
title_fullStr	Plasma cell survival in the absence of B cell memory
title_full_unstemmed	Plasma cell survival in the absence of B cell memory
title_sort	plasma cell survival in the absence of b cell memory
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1c247d33ca304c67924a5f0adaff21c2
work_keys_str_mv	AT erikahammarlund plasmacellsurvivalintheabsenceofbcellmemory AT archanathomas plasmacellsurvivalintheabsenceofbcellmemory AT ianjamanna plasmacellsurvivalintheabsenceofbcellmemory AT lindsayaholden plasmacellsurvivalintheabsenceofbcellmemory AT ovdslayden plasmacellsurvivalintheabsenceofbcellmemory AT byungpark plasmacellsurvivalintheabsenceofbcellmemory AT linagao plasmacellsurvivalintheabsenceofbcellmemory AT markkslifka plasmacellsurvivalintheabsenceofbcellmemory
_version_	1718389553211899904

Plasma cell survival in the absence of B cell memory

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