Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.

Daptomycin resistance in enterococci is associated with distinct alterations of cell membrane phospholipid content.

<h4>Background</h4>The lipopeptide antibiotic, daptomycin (DAP) interacts with the bacterial cell membrane (CM). Development of DAP resistance during therapy in a clinical strain of Enterococcus faecalis was associated with mutations in genes encoding enzymes involved in cell envelope ho...

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Autores principales: Nagendra N Mishra, Arnold S Bayer, Truc T Tran, Yousif Shamoo, Eugenia Mileykovskaya, William Dowhan, Ziqiang Guan, Cesar A Arias
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/1c28beb628d446718a33d82684844bc9
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