IPF-Fibroblast Erk1/2 Activity Is Independent from microRNA Cluster 17-92 but Can Be Inhibited by Treprostinil through DUSP1
Idiopathic pulmonary fibrosis (IPF) is a progressive terminal lung disease, and therapies aim to block fibrosis. Fibroblast proliferation is controlled by C/EBP-β, microRNA cluster 17-92 (miR17-92), and Erk1/2 mitogen-activated protein kinase. This study assessed the role of miR17-92 in IPF-fibrobla...
Guardado en:
Autores principales: | Sabrina Blumer, Lei Fang, Wei-Chih Chen, Petra Khan, Katrin Hostettler, Michael Tamm, Michael Roth, Christopher Lambers |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/1c3b0218fdf9491ea0dc4bc75a99dac4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases
por: Fatma Zohra Khoubai, et al.
Publicado: (2021) -
p70 Ribosomal Protein S6 Kinase Is a Checkpoint of Human Hepatic Stellate Cell Activation and Liver Fibrosis in MiceSummary
por: Florian P. Reiter, et al.
Publicado: (2022) -
Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells
por: Shun Nonoyama, et al.
Publicado: (2021) -
Stabilisation of Recombinant Human Basic Fibroblast Growth Factor (FGF-2) against Stressors Encountered in Medicinal Product Processing and Evaluation
por: Leah R. Benington, et al.
Publicado: (2021) -
Serum intact fibroblast growth factor 23 in healthy paediatric population
por: Stanczyk Malgorzata, et al.
Publicado: (2021)