SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

SPARC expression is associated with hepatic injury in rodents and humans with non-alcoholic fatty liver disease

Abstract Mechanisms that control progression from simple steatosis to steato-hepatitis and fibrosis in patients with non-alcoholic fatty liver disease (NAFLD) are unknown. SPARC, a secreted matricellular protein, is over-expressed in the liver under chronic injury. Contribution of SPARC accumulation...

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Autores principales: Guillermo Mazzolini, Catalina Atorrasagasti, Agostina Onorato, Estanislao Peixoto, Martin Schlattjan, Jan-Peter Sowa, Svenja Sydor, Guido Gerken, Ali Canbay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/1c427a079f5b42e8bf090c1de65c88de
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