Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children

Abstract Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domai...

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Autores principales:	Chun On Lee, Xiujuan Zhang, Nan Yuan, Shumin Tang, Li Jia Chen, Carol Y. Cheung, Jason C. Yam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/1c44215518cd49eb95d99a689895e094
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spelling	oai:doaj.org-article:1c44215518cd49eb95d99a689895e0942021-12-02T16:10:36ZComparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children10.1038/s41598-021-92980-92045-2322https://doaj.org/article/1c44215518cd49eb95d99a689895e0942021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92980-9https://doaj.org/toc/2045-2322Abstract Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domain optical coherence tomography (SD-OCT) and swept-source optical coherence tomography (SS-OCT) in healthy paediatric eyes. A total of 114 children from the population-based Hong Kong Children Eye Study with mean age of 7.38 ± 0.82 years were included. Choroidal thickness of the right eye was measured by both devices. The central foveal choroidal thickness (CFCT) measured by SD-OCT and SS-OCT was 273.24 ± 54.29 μm and 251.84 ± 47.12 μm respectively. Inter-device correlation coefficient was 0.840 (95% CI 0.616–0.918). However, choroidal thickness obtained by SD-OCT was significantly thicker than that measured by SS-OCT with a mean difference of 21.40 ± 33.13 μm (P < 0.001). Bland–Altman limit of agreement on the relative difference scale for SD-OCT/SS-OCT was 86.33 μm. Validated conversion equation for translating SD-OCT CFCT measurement into SS-OCT was SS-OCT = 35.261 + 0.810 × SD-OCT. In conclusion, intra-class correlation coefficient (ICC) shows an acceptable agreement between SD-OCT and SS-OCT, however, there was a significant inter-device difference of choroidal thickness measurements in normal children eyes. Therefore, the measurements are not interchangeable.Chun On LeeXiujuan ZhangNan YuanShumin TangLi Jia ChenCarol Y. CheungJason C. YamNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Chun On Lee Xiujuan Zhang Nan Yuan Shumin Tang Li Jia Chen Carol Y. Cheung Jason C. Yam Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
description	Abstract Choroidal thickness is associated with many ocular conditions, interchangeability among different generations of optical coherence tomography is therefore important for both research purpose and clinical application. Hence, we compared choroidal thickness measurements between spectral-domain optical coherence tomography (SD-OCT) and swept-source optical coherence tomography (SS-OCT) in healthy paediatric eyes. A total of 114 children from the population-based Hong Kong Children Eye Study with mean age of 7.38 ± 0.82 years were included. Choroidal thickness of the right eye was measured by both devices. The central foveal choroidal thickness (CFCT) measured by SD-OCT and SS-OCT was 273.24 ± 54.29 μm and 251.84 ± 47.12 μm respectively. Inter-device correlation coefficient was 0.840 (95% CI 0.616–0.918). However, choroidal thickness obtained by SD-OCT was significantly thicker than that measured by SS-OCT with a mean difference of 21.40 ± 33.13 μm (P < 0.001). Bland–Altman limit of agreement on the relative difference scale for SD-OCT/SS-OCT was 86.33 μm. Validated conversion equation for translating SD-OCT CFCT measurement into SS-OCT was SS-OCT = 35.261 + 0.810 × SD-OCT. In conclusion, intra-class correlation coefficient (ICC) shows an acceptable agreement between SD-OCT and SS-OCT, however, there was a significant inter-device difference of choroidal thickness measurements in normal children eyes. Therefore, the measurements are not interchangeable.
format	article
author	Chun On Lee Xiujuan Zhang Nan Yuan Shumin Tang Li Jia Chen Carol Y. Cheung Jason C. Yam
author_facet	Chun On Lee Xiujuan Zhang Nan Yuan Shumin Tang Li Jia Chen Carol Y. Cheung Jason C. Yam
author_sort	Chun On Lee
title	Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
title_short	Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
title_full	Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
title_fullStr	Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
title_full_unstemmed	Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
title_sort	comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/1c44215518cd49eb95d99a689895e094
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Comparison of choroidal thickness measurements between spectral domain optical coherence tomography and swept source optical coherence tomography in children

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