Motor neurons control blood vessel patterning in the developing spinal cord

The guidance cues regulating blood vessel patterning in the central nervous system remain unclear. Here, the authors show in mice and chicken developing spinal cord that motor neurons control blood vessel patterning by an autocrine mechanism titrating VEGF via the expression of its trapping receptor...

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Bibliographic Details
Main Authors: Patricia Himmels, Isidora Paredes, Heike Adler, Andromachi Karakatsani, Robert Luck, Hugo H. Marti, Olga Ermakova, Eugen Rempel, Esther T. Stoeckli, Carmen Ruiz de Almodóvar
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/1c485bbbb8e44bb3a721507f6d42678e
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