Effect of Administration of Moxifloxacin plus Rifampin against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> for 7 of 7 Days versus 5 of 7 Days in an <italic toggle="yes">In Vitro</italic> Pharmacodynamic System
ABSTRACT Some trials administered antituberculosis agents for 5 of 7 days (5/7-day regimen) to optimize adherence. Since moxifloxacin has a longer half-life than rifampin, rifampin concentrations are <1% of the maximum concentration in serum (Cmax) on day 6 and nondetectable on day 7, while conce...
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Autores principales: | G. L. Drusano, N. Sgambati, A. Eichas, D. Brown, R. Kulawy, A. Louie |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/1c54c34996e94dfda6cdb8f76184fbad |
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