A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

Research on the interactions between the gut microbiota and human cells would greatly benefit from improved in vitro models. Here, Shah et al. present a modular microfluidics-based model that allows co-culture of human and microbial cells followed by 'omic' molecular analyses of the two ce...

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Autores principales: Pranjul Shah, Joëlle V. Fritz, Enrico Glaab, Mahesh S. Desai, Kacy Greenhalgh, Audrey Frachet, Magdalena Niegowska, Matthew Estes, Christian Jäger, Carole Seguin-Devaux, Frederic Zenhausern, Paul Wilmes
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/1c551f94bc624ad09b8ba6bc26235186
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spelling oai:doaj.org-article:1c551f94bc624ad09b8ba6bc262351862021-12-02T17:31:20ZA microfluidics-based in vitro model of the gastrointestinal human–microbe interface10.1038/ncomms115352041-1723https://doaj.org/article/1c551f94bc624ad09b8ba6bc262351862016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11535https://doaj.org/toc/2041-1723Research on the interactions between the gut microbiota and human cells would greatly benefit from improved in vitro models. Here, Shah et al. present a modular microfluidics-based model that allows co-culture of human and microbial cells followed by 'omic' molecular analyses of the two cell contingents.Pranjul ShahJoëlle V. FritzEnrico GlaabMahesh S. DesaiKacy GreenhalghAudrey FrachetMagdalena NiegowskaMatthew EstesChristian JägerCarole Seguin-DevauxFrederic ZenhausernPaul WilmesNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pranjul Shah
Joëlle V. Fritz
Enrico Glaab
Mahesh S. Desai
Kacy Greenhalgh
Audrey Frachet
Magdalena Niegowska
Matthew Estes
Christian Jäger
Carole Seguin-Devaux
Frederic Zenhausern
Paul Wilmes
A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
description Research on the interactions between the gut microbiota and human cells would greatly benefit from improved in vitro models. Here, Shah et al. present a modular microfluidics-based model that allows co-culture of human and microbial cells followed by 'omic' molecular analyses of the two cell contingents.
format article
author Pranjul Shah
Joëlle V. Fritz
Enrico Glaab
Mahesh S. Desai
Kacy Greenhalgh
Audrey Frachet
Magdalena Niegowska
Matthew Estes
Christian Jäger
Carole Seguin-Devaux
Frederic Zenhausern
Paul Wilmes
author_facet Pranjul Shah
Joëlle V. Fritz
Enrico Glaab
Mahesh S. Desai
Kacy Greenhalgh
Audrey Frachet
Magdalena Niegowska
Matthew Estes
Christian Jäger
Carole Seguin-Devaux
Frederic Zenhausern
Paul Wilmes
author_sort Pranjul Shah
title A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
title_short A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
title_full A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
title_fullStr A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
title_full_unstemmed A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
title_sort microfluidics-based in vitro model of the gastrointestinal human–microbe interface
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/1c551f94bc624ad09b8ba6bc26235186
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