A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy
Tumor hypoxia is a major limitation in radiotherapy, and strategies to address this often fail due to high oxygen consumption. Here, the authors report a nanomaterial assembly for the simultaneous reduction in mitochondrial respiration and to supply oxygen to potentiate radiotherapy.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/1c58c1e0a770416a88be21da7c575243 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:1c58c1e0a770416a88be21da7c575243 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:1c58c1e0a770416a88be21da7c5752432021-12-02T13:51:14ZA hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy10.1038/s41467-020-20860-32041-1723https://doaj.org/article/1c58c1e0a770416a88be21da7c5752432021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20860-3https://doaj.org/toc/2041-1723Tumor hypoxia is a major limitation in radiotherapy, and strategies to address this often fail due to high oxygen consumption. Here, the authors report a nanomaterial assembly for the simultaneous reduction in mitochondrial respiration and to supply oxygen to potentiate radiotherapy.Wei TangZhen YangLiangcan HeLiming DengParinaz FathiShoujun ZhuLing LiBo ShenZhantong WangOrit JacobsonJibin SongJianhua ZouPing HuMin WangJing MuYaya ChengYuanyuan MaLongguang TangWenpei FanXiaoyuan ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Wei Tang Zhen Yang Liangcan He Liming Deng Parinaz Fathi Shoujun Zhu Ling Li Bo Shen Zhantong Wang Orit Jacobson Jibin Song Jianhua Zou Ping Hu Min Wang Jing Mu Yaya Cheng Yuanyuan Ma Longguang Tang Wenpei Fan Xiaoyuan Chen A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| description |
Tumor hypoxia is a major limitation in radiotherapy, and strategies to address this often fail due to high oxygen consumption. Here, the authors report a nanomaterial assembly for the simultaneous reduction in mitochondrial respiration and to supply oxygen to potentiate radiotherapy. |
| format |
article |
| author |
Wei Tang Zhen Yang Liangcan He Liming Deng Parinaz Fathi Shoujun Zhu Ling Li Bo Shen Zhantong Wang Orit Jacobson Jibin Song Jianhua Zou Ping Hu Min Wang Jing Mu Yaya Cheng Yuanyuan Ma Longguang Tang Wenpei Fan Xiaoyuan Chen |
| author_facet |
Wei Tang Zhen Yang Liangcan He Liming Deng Parinaz Fathi Shoujun Zhu Ling Li Bo Shen Zhantong Wang Orit Jacobson Jibin Song Jianhua Zou Ping Hu Min Wang Jing Mu Yaya Cheng Yuanyuan Ma Longguang Tang Wenpei Fan Xiaoyuan Chen |
| author_sort |
Wei Tang |
| title |
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| title_short |
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| title_full |
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| title_fullStr |
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| title_full_unstemmed |
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| title_sort |
hybrid semiconducting organosilica-based o2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/1c58c1e0a770416a88be21da7c575243 |
| work_keys_str_mv |
AT weitang ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT zhenyang ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT liangcanhe ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT limingdeng ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT parinazfathi ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT shoujunzhu ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT lingli ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT boshen ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT zhantongwang ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT oritjacobson ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jibinsong ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jianhuazou ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT pinghu ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT minwang ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jingmu ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT yayacheng ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT yuanyuanma ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT longguangtang ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT wenpeifan ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT xiaoyuanchen ahybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT weitang hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT zhenyang hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT liangcanhe hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT limingdeng hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT parinazfathi hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT shoujunzhu hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT lingli hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT boshen hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT zhantongwang hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT oritjacobson hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jibinsong hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jianhuazou hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT pinghu hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT minwang hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT jingmu hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT yayacheng hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT yuanyuanma hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT longguangtang hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT wenpeifan hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy AT xiaoyuanchen hybridsemiconductingorganosilicabasedo2nanoeconomizerforondemandsynergisticphotothermallyboostedradiotherapy |
| _version_ |
1718392424552726528 |