Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

Abstract The rising prevalence of chronic liver disease, coupled with a permanent shortage of organs for liver transplantation, has sparked enormous interest in alternative treatment strategies. Previous protocols to generate hepatocyte-like cells (HLCs) via pancreas-to-liver transdifferentiation ha...

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Autores principales: Francis D. Gratte, Sara Pasic, John K. Olynyk, George C. T. Yeoh, David Tosh, Deirdre R. Coombe, Janina E. E. Tirnitz-Parker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/1c6f068c1e694afea2169b275e22b469
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