Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins
Abstract The rising prevalence of chronic liver disease, coupled with a permanent shortage of organs for liver transplantation, has sparked enormous interest in alternative treatment strategies. Previous protocols to generate hepatocyte-like cells (HLCs) via pancreas-to-liver transdifferentiation ha...
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Autores principales: | Francis D. Gratte, Sara Pasic, John K. Olynyk, George C. T. Yeoh, David Tosh, Deirdre R. Coombe, Janina E. E. Tirnitz-Parker |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/1c6f068c1e694afea2169b275e22b469 |
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