The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient

Introduction: Leprosy reaction is an immunity declining reaction marked with inflammation which may cause permanent disability. Physical exercise may improve body’s immune system. Objective: To prove the effect of moderate-intensity physical exercise on the interleukin-6 level and lymphocyte count i...

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Autores principales:	Adryan Roy, Taufiqurrachman Nasihun, Titiek Sumarawati
Formato:	article
Lenguaje:	EN
Publicado:	Universitas Sultan Agung Semarang 2021
Materias:	moderate-intensity exercise il-6 lymphocyte Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/1c74d455dbd24364991be9c2e1490888
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spelling	oai:doaj.org-article:1c74d455dbd24364991be9c2e14908882021-11-25T13:16:54ZThe Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient2085-15452339-093X10.30659/sainsmed.v12i1.11931https://doaj.org/article/1c74d455dbd24364991be9c2e14908882021-05-01T00:00:00Zhttp://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/11931https://doaj.org/toc/2085-1545https://doaj.org/toc/2339-093XIntroduction: Leprosy reaction is an immunity declining reaction marked with inflammation which may cause permanent disability. Physical exercise may improve body’s immune system. Objective: To prove the effect of moderate-intensity physical exercise on the interleukin-6 level and lymphocyte count in leprosy reaction patient. Methods: The quasi-experimental research with pretest and posttest and a control group design used 30 respondents consisting of 14 interventions and 16 controls. The intervention group was given moderate-intensity physical exercise 60%-79% in the form of static cycle at a frequency of 4 times weekly, 150 minutes per week. Corticosteroid was always administered to the two groups as a standard therapy. The interleukin-6 level was measured using ELISA method and lymphocyte count was measured using hematology analyzer. Result: The Mann-Whitney analysis shows that the mean difference in IL-6 level between pretest and posttest with the intervention group (-7.1429±25.2369) is significantly lower than that of the control group (8.8125±11.2025), p<0.05. On the contrary, the Independent t-test analysis shows that the mean difference in lymphocyte count between pretest and posttest with the intervention group (0.7407±0.41236) is significantly higher than that of the control group (-0.4500±0.42415), p<0.05. Conclusion: Physical exercise at moderate intensity in the form of aerobics using static cycle at a frequency of 4 times weekly, with duration of 150 minutes per week decreases interleukin-6 level and increases lymphocyte count in leprosy reaction patient.Adryan RoyTaufiqurrachman NasihunTitiek SumarawatiUniversitas Sultan Agung Semarangarticlemoderate-intensity exerciseil-6lymphocyteMedicine (General)R5-920ENSains Medika, Vol 12, Iss 1, Pp 19-25 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	moderate-intensity exercise il-6 lymphocyte Medicine (General) R5-920
spellingShingle	moderate-intensity exercise il-6 lymphocyte Medicine (General) R5-920 Adryan Roy Taufiqurrachman Nasihun Titiek Sumarawati The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
description	Introduction: Leprosy reaction is an immunity declining reaction marked with inflammation which may cause permanent disability. Physical exercise may improve body’s immune system. Objective: To prove the effect of moderate-intensity physical exercise on the interleukin-6 level and lymphocyte count in leprosy reaction patient. Methods: The quasi-experimental research with pretest and posttest and a control group design used 30 respondents consisting of 14 interventions and 16 controls. The intervention group was given moderate-intensity physical exercise 60%-79% in the form of static cycle at a frequency of 4 times weekly, 150 minutes per week. Corticosteroid was always administered to the two groups as a standard therapy. The interleukin-6 level was measured using ELISA method and lymphocyte count was measured using hematology analyzer. Result: The Mann-Whitney analysis shows that the mean difference in IL-6 level between pretest and posttest with the intervention group (-7.1429±25.2369) is significantly lower than that of the control group (8.8125±11.2025), p<0.05. On the contrary, the Independent t-test analysis shows that the mean difference in lymphocyte count between pretest and posttest with the intervention group (0.7407±0.41236) is significantly higher than that of the control group (-0.4500±0.42415), p<0.05. Conclusion: Physical exercise at moderate intensity in the form of aerobics using static cycle at a frequency of 4 times weekly, with duration of 150 minutes per week decreases interleukin-6 level and increases lymphocyte count in leprosy reaction patient.
format	article
author	Adryan Roy Taufiqurrachman Nasihun Titiek Sumarawati
author_facet	Adryan Roy Taufiqurrachman Nasihun Titiek Sumarawati
author_sort	Adryan Roy
title	The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
title_short	The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
title_full	The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
title_fullStr	The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
title_full_unstemmed	The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient
title_sort	effect of moderate-intensity physical exercise on interleukin-6 level and lymphocyte count in leprosy reaction patient
publisher	Universitas Sultan Agung Semarang
publishDate	2021
url	https://doaj.org/article/1c74d455dbd24364991be9c2e1490888
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The Effect of Moderate-Intensity Physical Exercise on Interleukin-6 Level and Lymphocyte Count in Leprosy Reaction Patient

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